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Characterization of a 4,6???glucanotransferase from Lactobacillus reuteri E81 and production of malto-oligosaccharides with immune-modulatory roles 

İspirli H.; Şimşek Ö.; Skory C.; Sağdıç O.; Dertli E. (Elsevier B.V., 2019)
A wide number of Lactic Acid Bacteria (LAB) species produce ?-glucans with their ability to synthesize glucansucrases (GS) which use sucrose as substrate for the glucan production. Recently another group of enzymes in LAB ...

Synthesis of Enantiomerically Enriched Drug Precursors by Lactobacillus paracasei BD87E6 as a Biocatalyst 

Öksüz S.; Şahin E.; Dertli E. (Wiley-VCH Verlag, 2018)
Global sales of single enantiomeric drug products are growing at an alarming rate every year. A total of 7 bacterial strains were screened for their ability to reduce acetophenones to its corresponding alcohol. Among these ...

Genome sequences of five Lactobacillus sp. isolates from traditional Turkish sourdough 

Dertli E.; Skory C.D.; Şimşek Ö. (American Society for Microbiology, 2018)
A high level of variation in microflora can be observed in profiles of lactic acid bacteria (LAB) from sourdoughs. Here, we present draft genome sequences of Lactobacillus reuteri E81, L. reuteri LR5A, L. rhamnosus LR2, ...

Highly Enantioselective Production of Chiral Secondary Alcohols Using Lactobacillus paracasei BD101 as a New Whole Cell Biocatalyst and Evaluation of Their Antimicrobial Effects 

Yılmaz D.; Şahin E.; Dertli E. (Wiley-VCH Verlag, 2017)
Chiral secondary alcohols are valuable intermediates for many important enantiopure pharmaceuticals and biologically active molecules. In this work, we studied asymmetric reduction of aromatic ketones to produce the ...

Highly Enantioselective Production of Chiral Secondary Alcohols with Candida zeylanoides as a New Whole Cell Biocatalyst 

Şahin E.; Dertli E. (Wiley-VCH Verlag, 2017)
The increasing demand for biocatalysts in synthesizing enantiomerically pure chiral alcohols results from the outstanding characteristics of biocatalysts in reaction, economic, and ecological issues. Herein, fifteen yeast ...

EpsA is an essential gene in exopolysaccharide production in Lactobacillus johnsonii FI9785 

Dertli E.; Mayer M.J.; Colquhoun I.J.; Narbad A. (John Wiley and Sons Ltd, 2016)
Lactobacillus johnsonii FI9785 has an eps gene cluster which is required for the biosynthesis of homopolymeric exopolysaccharides (EPS)-1 and heteropolymeric EPS-2 as a capsular layer. The first gene of the cluster, epsA, ...

Impact of exopolysaccharide production on functional properties of some Lactobacillus salivarius strains 

Mercan E.; İspirli H.; Sert D.; Yılmaz M.T.; Dertli E. (Springer Verlag, 2015)
The aim of this work was to characterize functional properties of Lactobacillus salivarius strains isolated from chicken feces. Detection of genes responsible for exopolysaccharide (EPS) production revealed that all strains ...

Characterization of functional properties of enterococcus faecium strains isolated from human gut 

İspirli H.; Demirbaş F.; Dertli E. (National Research Council of Canada, 2015)
The aim of this work was to characterize the functional properties of Enterococcus faecium strains identified after isolation from human faeces. Of these isolates, strain R13 showed the best resistance to low pH, bile ...

Impact of the exopolysaccharide layer on biofilms, adhesion and resistance to stress in Lactobacillus johnsonii FI9785 

Dertli E.; Mayer M.J.; Narbad A. (BioMed Central Ltd., 2015)
Background: The bacterial cell surface is a crucial factor in cell-cell and cell-host interactions. Lactobacillus johnsonii FI9785 produces an exopolysaccharide (EPS) layer whose quantity and composition is altered in ...

Structure and biosynthesis of two exopolysaccharides produced by lactobacillus johnsonii FI9785 

Dertli E.; Colquhoun I.J.; Gunning A.P.; Bongaerts R.J.; Le Gall G.; Bonev B.B.; Mayer M.J.; Narbad A. (2013)
Exopolysaccharides were isolated and purified from Lactobacillus johnsonii FI9785, which has previously been shown to act as a competitive exclusion agent to control Clostridium perfringens in poultry. Structural analysis ...
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