Yazar "6603903192" için WoS İndeksli Yayınlar Koleksiyonu listeleme
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Carbonic anhydrase activity from the gilthead sea bream (Sparus aurata) liver: The toxicological effects of heavy metals
Kaya E.D.; Söyüt H.; Beydemir T. (2013)Many studies have shown that metal ions may lead to oxidative stress in biological systems. Accordingly, DNA damage, protein modification, enzyme inhibition and activation, lipid peroxidation and many other effects may ... -
Changes in carbonic anhydrase activity and gene expression of Hsp70 in rainbow trout (Oncorhynchus mykiss) muscle after exposure to some metals
Söyüt H.; Beydemir S.; Ceyhun S.B.; Erdo?an O.; Kaya E.D. (2012)The effects of some heavy metals Co(II), Cu(II), Zn(II), and Ag(I) on carbonic anhydrase (CA) activity from rainbow trout (RT) muscle were investigated. Moreover, the effects of these metals on the expression of heat shock ... -
Effect of calcium channel blockers on paraoxonase-1 (PON1) activity and oxidative stress
Türkeş C.; Söyüt H.; Beydemir S. (Elsevier B.V., 2014)Background: In this study, we investigated the in vitro effects of calcium channel blockers (nifedipine, nitrendipine, isradipine, and amlodipine besylate) on the activity of paraoxonase-1 (PON1). Methods: PON1 was purified ... -
Human serum paraoxonase-1 (hPON1): In vitro inhibition effects of moxifloxacin hydrochloride, levofloxacin hemihidrate, cefepime hydrochloride, cefotaxime sodium and ceftizoxime sodium
Türkeş C.; Söyüt H.; Beydemir Ş. (Taylor and Francis Ltd, 2015)In this study, we investigated the effects of antibacterial drugs (moxifloxacin hydrochloride, levofloxacin hemihidrate, cefepime hydrochloride, cefotaxime sodium and ceftizoxime sodium) on human serum paraoxonase-1 (hPON1) ... -
The impact of heavy metals on the activity of carbonic anhydrase from rainbow trout (Oncorhynchus mykiss) kidney
Söyüt H.; Beydemir S. (2012)Many environmental and health problems have become a consequence of contamination of soil and water by toxic heavy metals and organic pollutants in the present age of technology. Heavy metals play vital roles in enzyme ... -
In vitro inhibitory effects of palonosetron hydrochloride, bevacizumab and cyclophosphamide on purified paraoxonase-I (hPON1) from human serum
Türkeş C.; Söyüt H.; Beydemir S. (Elsevier B.V., 2016)In this study, we investigated the effects of the drugs, palonosetron hydrochloride, bevacizumab and cyclophosphamide, on human serum paraoxonase-I (hPON1) enzyme activity in in vitro conditions. The enzyme was purified ... -
Inhibition behaviours of some phenolic acids on rat kidney aldose reductase enzyme: an in vitro study
Alim Z.; Kilinç N.; Şengül B.; Beydemir Ş. (Taylor and Francis Ltd, 2017)Aldose reductase (AR) inhibitors have vital importance in the treatment and prevention of diabetic complications. In this study, rat kidney AR was purified 19.34-fold with a yield of 3.49% and a specific activity of 0.88 ... -
The interactions of cephalosporins on polyol pathway enzymes from sheep kidney
Şengül B.; Beydemir Ş. (Taylor and Francis Ltd, 2018)Context: Cephalosporins are derived from the fungus Acremonium. Due to their strong bactericidal ability, these drugs have to a wide usage in medicine. Objective: An investigation of the effects on sheep renal aldose ... -
Mechanism of capsaicin inhibition of aldose reductase activity
Alim Z.; Kilinc N.; Sengul B.; Beydemir S. (John Wiley and Sons Inc., 2017)Aldose reductase (AR) inhibitors play a vital importance as a potential therapeutic and preventive medicine when it comes to hyperglycemia associated diabetic complications. Additionally, capsaicin is used as a food additive ... -
Synthesis and carbonic anhydrase inhibitory properties of novel bromophenols including natural products
Balaydiin H.T.; Soyut H.; Ekinci D.; Göksu S.; Beydemir S.; Menzek A.; Şahin E. (2012)(2-Bromo-3,4-dimethoxyphenyl) (3,4-dimethoxyphenyl)methanone (10) and its derivatives with Br, one dibromide and isomeric three tribromides, were synthesized. Demethylation of these compounds afforded a series of new ... -
The toxicological impacts of some heavy metals on carbonic anhydrase from gilthead sea bream (Sparus aurata) gills
Kaya E.D.; Söyüt H.; Beydemir Ş. (Elsevier, 2015)It is known that heavy metals have toxic effects on fish. Insufficient measures are a serious problem in our country and around the world. This problem can threaten human health in areas where it is common for people to ...