dc.contributor.author | Şahin, Engin | |
dc.contributor.author | Kılıç, Hamdullah | |
dc.contributor.author | Törnük. Fatih | |
dc.contributor.author | Dertli, Enes | |
dc.date.accessioned | 2020-11-25T19:52:15Z | |
dc.date.available | 2020-11-25T19:52:15Z | |
dc.date.issued | 2019 | en_US |
dc.identifier.citation | Şahin, E., Kılıç, H., Törnük, F., & Dertli, E. (2019). Synthesis and Biological Evaluation of Novel Tricyclic Pyrrolidinyl (R)‐Alcohols and Amines. Journal of Heterocyclic Chemistry, 56(3), 824-831. | en_US |
dc.identifier.uri | https://onlinelibrary.wiley.com/doi/full/10.1002/jhet.3457?casa_token=zuxeh-nbvnUAAAAA%3A1BEYYliDjIwmXU0NhhNU28BAT6e49Naw_wux7uDsQ0MKwCPpvqHw_hHG6ilqUa8xQbi2UQcXm4r1o8Ws | |
dc.identifier.uri | https://hdl.handle.net/20.500.12403/2227 | |
dc.description.abstract | Three new tricyclic pyrrolidinyl alcohols and three tricyclic pyrrolidinyl amines were synthesized, and the antibacterial activities of these compounds were tested against Salmonella enterica subsp. enterica serovar Typhimurium, Escherichia coli O157:H7, Staphylococcus aureus, and Listeria monocytogenes. All tested pyrrolidinyl alcohols and amines showed antibacterial activity to the tested pathogens, but this activity was dependent on the final concentration of the tested compound, and the structure of these compounds were also important for this antibacterial activity. Of the tested compounds, (2R)‐2‐(octahydro‐4,8‐ethanocyclohepta[c]pyrrol‐2(1H)‐yl)‐2‐phenylethanamine (2c) was the most effective compound among the tested pyrrolidinyl alcohols and amines. This study shows a good example of finding new antimicrobials in order to control pathogenic bacteria. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | The Journal of Heterocyclic Chemistry | en_US |
dc.relation.isversionof | 10.1002/jhet.3457 | en_US |
dc.subject | antibacterial activity | en_US |
dc.subject | amino alcohol | en_US |
dc.subject | tricyclic pyrrolidinyl alcohols | en_US |
dc.title | Synthesis and Biological Evaluation of Novel Tricyclic Pyrrolidinyl (R)‐Alcohols and Amines | en_US |
dc.type | article | en_US |
dc.relation.journal | The Journal of Heterocyclic Chemistry | en_US |
dc.contributor.department | Bayburt Üniversitesi, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümü | en_US |
dc.contributor.authorID | 0000-0002-3723-1705 | en_US |
dc.identifier.volume | 56 | en_US |
dc.identifier.issue | 63 | en_US |
dc.identifier.startpage | 824 | en_US |
dc.identifier.endpage | 831 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |