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Öğe Anti-genotoxic Effects of Schiff bases and their Mn(III) Complexes Containing L-Aspartic acid and L-Phenylalanine(Gazi Univ, 2018) Hasanoglu Ozkan, Elvan; Kizil, Hamit Emre; Sakiyan, Iffet; Nartop, Dilek; Sari, Nursen; Agar, GulerayThe purpose of the research was to evaluate the genotoxic and anti-genotoxic properties of Schiff bases and their Mn (III) complexes containing L-aspartic acid, and L-phenylalanine. The anti-genotoxic properties of four compounds in human lymphocytes cells were investigated by sister chromatid exchanges (SCEs) test system against aflatoxin Bi (AFBi). The results showed that compounds have strong anti-genotoxic properties.Öğe Antiproliferative and apoptotic properties of vulpinic acid on A549, AGS and HeLa cells(Elsevier Science Bv, 2017) Kizil, Hamit Emre; Agar, Guleray[Abstract Not Available]Öğe Antiproliferative effects of Evernic acid on A549 and healthy human cells: An in vitro study(Elsevier Science Bv, 2015) Kizil, Hamit Emre; Agar, Guleray; Anar, Mustafa[Abstract Not Available]Öğe Cytotoxic and antiproliferative effects of evernic acid on HeLa cell lines: A candidate anticancer drug(Elsevier Science Bv, 2014) Kizil, Hamit Emre; Agar, Guleray; Anar, Mustafa[Abstract Not Available]Öğe DETERMINATION OF ANTIGENOTOXIC EFFECTS OF FOUR LICHEN SPECIES BY USING HUMAN LYMPHOCYTES(Parlar Scientific Publications (P S P), 2015) Anar, Mustafa; Aslan, Ali; Ceker, Selcuk; Kizil, Hamit Emre; Alpsoy, Lokman; Agar, GulerayIn this study, the geno-toxic and antigeno-toxic properties of the total extracts of four lichen species were investigated by using human lymphocytes. We obtained total extracts from R. farinacea, X parietina, U articulata and U. filipendula lichen species. The results of our studies showed that 5 mu M concentrations of AFB(1) changed the frequencies of micronucleus (MN) and malondialdehyde (MDA) levels, as well as superoxide dismutase (SOD), glutathione (GSH) and glutathione peroxidase (GPx) activities. When 5, 10 and 20 mu g/ml concentrations of total extract were added to AFB(1), the frequencies of MN and MDA levels were decreased, and SOD, GSH and GPx levels were increased. Consequently, our findings show that four lichen total extracts have strong antigenotoxic properties against aflatoxin B-1.Öğe The determination of antioxidative effect and anticancer potential of vulpinic acid(Elsevier Science Bv, 2014) Anar, Mustafa; Kizil, Hamit Emre; Agar, Guleray[Abstract Not Available]Öğe Determination of cytotoxic and proliferative effects of 2-amino-5-nitrobenzonitrile on AGS cancer cell line(Elsevier Science Bv, 2015) Anar, Mustafa; Kizil, Hamit Emre; Agar, Guleray[Abstract Not Available]Öğe Determination of the Antigenotoxic effects of Evernic acid against genotoxic effects of CCL4 on HUVEC lines(Elsevier Science Bv, 2017) Agar, Guleray; Kizil, Hamit Emre; Ceker, Selcuk; Capik, Ozel; Sengul, Bulent[Abstract Not Available]
