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Öğe The effect of bed exercises following major abdominal surgery on early ambulation, mobilization, pain and anxiety: A randomized-controlled trial(Wiley, 2024) Yaban, Zuleyha Simsek; Bulbuloglu, Semra; Kapikiran, Gurkan; Gunes, Huseyin; Sahin, Sennur Kula; Saritas, SerdarThis randomized-controlled trial aimed to investigate the effect of bed exercises on postoperative anxiety, pain, early ambulation and mobilization. This study was conducted with a randomized-controlled trial design and in the general surgical clinic of a research and training hospital. A total of 120 patients (60 in the experimental group and 60 in the control group) scheduled for major abdominal surgery took part in the study. The data were collected using a patient information form, the Anxiety Specific to Surgery Questionnaire and the Visual Analog Scale through face-to-face interviews. The patients in the experimental group performed 15-min bed exercises on the day of their operation, as well as on the postoperative first and second days, and the control group underwent only the routinely performed procedures in the clinic. The data were analysed using descriptive statistics, analysis of variance and t-tests. The sample of our study included major abdominal surgery patients. Ambulation was achieved at a mean time of 4 h earlier in the experimental group. On the postoperative first and second days, the patients in the experimental group had mean mobilization durations that were approximately 2 h longer compared with the patients in the control group. Moreover, the postoperative pain and anxiety levels of the patients in the experimental group were significantly lower than those of the patients in the control group (p < 0.05). We recommend that bed exercises be performed to lower anxiety and pain severity, achieve early ambulation and increase the duration of mobilization among patients following major abdominal surgery.Öğe Investigation of adherence to immunosuppressive therapy and spiritual well-being in liver recipients(Elsevier, 2022) Gunes, Huseyin; Bulbuloglu, Semra; Saritas, SerdarObjective: In our study, we investigated the relationship between spiritual well-being and adherence to immunosuppressive therapy after liver transplantation. Method: We conducted this descriptive and cross-sectional study with the participation of 131 liver transplant recipients after they had received their transplants. Data collection was carried out using a Personal Information Form, the Spiritual Well-Being Scale and the Immunosuppressant Therapy Adherence Scale. The IBM Statistical Package for the Social Sciences 25.0 was used for the statistical analyses. Results: While 73.3% of the patients were at the ages of 45-64, 72.5% were male, and 39.7% had been using immunosuppressive medication for a period between 6 months and 1 year. The rate of corticosteroid use among the patients was 30.5%, and the rate of antimetabolite use was 21.4%. A positive and significant relationship was found between adherence to immunosuppressive treatment and spiritual well-being (B = 0.425, p = 0.017). Conclusion: Spiritual well-being is an inexpensive, effective and easy strategy to increase adherence to immunosuppressive treatment. Awareness should be raised in physicians and nurses about the importance of spiritual well-being, and they should be encouraged to support spiritual well-being.Öğe Investigation of life satisfaction and spiritual well-being of living liver donors in Turkey(Springer, 2025) Gunes, Huseyin; Bulbuloglu, Semra; Saritas, SerdarSpiritual well-being may be among the most common feelings felt by living liver donors. The feeling that pushes an individual to good behavior may be spiritual well-being, and the feeling that emerges as a result of achieving goodness may be life satisfaction. In our study, we aimed to analyze the spiritual well-being and life satisfaction of living liver donors and to examine the relationship, if any, between spiritual well-being and life satisfaction. Our descriptive and cross-sectional study was conducted with 306 living liver donors (n = 306). In the data collection process, we used a personal information form, the Spiritual Well-Being Scale, and the Satisfaction with Life Scale. In data analysis, we utilized descriptive statistical methods, one-way analysis of variance. Of all living liver donors participating in this study, 37.3% were aged 41-50 years, 73.5% were female, and 53.9% donated their liver to their spouse or child. The predictor variable of spiritual well-being was found to account for approximately 29% of the total variance in the predicted variable of life satisfaction. There was a positive and strong correlation between spiritual well-being and life satisfaction of living liver donors (p < 0.05). Spiritual well-being and life satisfaction of living liver donors are positively affected by each other. In order to provide more psychosocial support to these heroes who disregard their own health and try to save others' lives, it is best practice to support their spiritual well-being, increase their life satisfaction and develop awareness about these two values. No Level Assigned. This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/0026.Öğe Investigation of Post-Transplant Mental Well-Being in Liver Transplant Recipients with Hepatic Encephalopathy(Mdpi, 2024) Saritas, Serdar; Tarlaci, Sultan; Bulbuloglu, Semra; Gunes, HuseyinObjective: In this study, we aimed to examine the healing trend of hepatic encephalopathy after transplantation surgery in patients with liver failure. Method: We conducted this descriptive and cross-sectional study with the participation of liver transplant recipients. A personal information form, the West Haven Criteria (WHC), the Warwick-Edinburgh Mental Well-Being Scale (WEMWBS), and the Richmond Agitation Sedation Scale (RASS) were used for data collection. The data were analyzed using Chi-squared tests, ANOVA, and paired-samples t-tests. Results: As time progressed after liver transplantation, hepatic encephalopathy stages regressed (p < 0.01). We found that liver transplant recipients with end-stage hepatic encephalopathy were mostly within the first 6 months after transplantation, while patients with first-stage hepatic encephalopathy had received liver transplants more than 2 years ago (p < 0.01). Conclusions: The results of our study revealed that hepatic encephalopathy stages regressed after transplantation, but there was no complete recovery. This highlights the need to develop new treatment strategies other than liver transplantation for the treatment of hepatic encephalopathy.Öğe Mindfulness-based cognitive therapy for adherence of immunosuppressive treatment in liver transplant recipients: A randomized controlled trial(Elsevier Science Inc, 2024) Bulbuloglu, Semra; Gunes, HuseyinObjective: The aim of this study was to analyze the effects of mindfulness-based cognitive therapy on the adherence of liver transplant recipients to immunosuppressive therapy with a randomized controlled design. Method: This randomized controlled trial was performed with 120 liver transplant recipients hospitalized at the liver transplant department of a research and practice hospital (n = 120). While we administered no intervention to the patients in the control group (n = 60), we provided Mindfulness-Based Cognitive Therapy to those in the experimental group (n = 60). We used the Mindful Attention Awareness Scale and the Immunosuppressant Therapy Adherence Scale to collect data. We utilized descriptive statistics, paired-samples t-tests, independent samples t-tests, one-way analysis of variance, and chi-squared tests to analyze the data. Results: After the intervention, the immunosuppressive therapy adherence levels of the experimental group increased significantly (p < 0.01). On the other hand, the control group had significantly higher adherence to immunosuppressive therapy and significantly higher levels of mindfulness in the pretest phase than it did in the posttest phase (p < 0.01). Conclusions: Complete adherence to immunosuppressive therapy is imperative for the prevention of graft rejection in liver transplant recipients. In our study, the experimental group equipped with enhanced mindfulness had higher adherence to immunosuppressive therapy. Therefore, the use of Mindfulness-Based Cognitive Therapy in the promotion of adherence to immunosuppressive therapy is recommended.Öğe A randomized controlled trial of reflexology effect after abdominal surgery on patient satisfaction, pain and vital signs(Elsevier Science Inc, 2023) Kapikiran, Guerkan; Bulbuloglu, Semra; Gunes, Huseyin; Saritas, Serdar; Demir, BilsevObjective: In our study, we investigated the effect of reflexology on patient satisfaction, pain and vital signs after abdominal surgery.Method: This study was conducted as a randomized controlled trial with the participation of 156 abdominal surgery patients hospitalized in the general surgery unit of a training and research hospital. Personal Information Form, Visual Analogue Scale and Newcastle Nursing Care Satisfaction Scale were used in data collection. We performed the data analysis with One-way analysis of variance, Chi-squared test, paired samples t-test, and independent samples t-test.Results: When the pain, vital signs and satisfaction levels of the experimental and control groups were compared, the pain intensity of the experimental group was found to be lower and the level of satisfaction was higher after reflexology (p<0.01). After reflexology, the blood pressure was closer to 120/80 in the experimental group, the respiratory rate was between 16-22 (number/minute), the difference between the experimental and control groups were statistically significant (p<0.01). There was no statistically significant difference between the pulce oximetry values between the experimental and control groups.Conclusion: Surgical pain and non-optimal vital signs that are not well managed after surgery causes various complications and decrease patient satisfaction. The results of our study emphasize the power of reflexology in effective surgical pain management and normalizing vital signs and increasing patient satisfaction. We suggest that reflexology be performed to patients following abdominal surgery.Öğe Relation between monocyte to high-density lipoprotein cholesterol ratio and prognosis in recipients after liver transplantation(Elsevier, 2025) Okutan, Serafettin; Saritas, Hasan; Saritas, Serdar; Bulbuloglu, Semra; Gunes, HuseyinBackground The end-stage liver diseases require liver transplantation as the life-saving solution. It is known that monocytes/macrophages and high-density lipoprotein cholesterol (HDLC) have important contributions to the development of hepatic inflammation and oxidative stress before liver transplantation. However, the effect of monocyte/HDL-C ratio (MHR) on clinical progression and outcome in the post-transplant period are not fully understood. Our hypothesis is that the MHR value may be associated with poor vs. good outcomes after liver transplantation. Methods In our retrospective study, we included 464 liver transplant recipients. Patients' data were extracted from electronic and other paper records in our teaching/research hospital. The MHR values and other blood parameters (creatinine, total protein, albumin, etc.) were expressed as a mean and standard deviation, which were analyzed by the Pearson correlation test. The relationship between graft dysfunction and MHR was determined by ROC curve analysis. Results The mean age of liver transplant recipients was 45.8 +/- 13.7 years. Nineteen percent of patients had liver failure due to Alcoholic Fatty Liver Disease (AFLD) and 34.5 % had liver failure due to hepatitis B virus. At the end of 3 months after liver transplantation, 84.5 % of liver transplant recipients were alive, 5.8 % experienced graft rejection and 5.17 % had an infection. There was a statistically significant improvement in total protein, albumin, liver function tests, and serum creatinine values of the survivors (all p < 0.05). The MHR levels were significantly higher in patients who died after transplantation in comparison to those who survived before and after liver transplantation and these differences were statistically significant (p < 0.01). Conclusion The increased MHR values of recipients after liver transplantation correlated with their risk of survival. Furthermore, the MHR value increased with increased MELD score and the number of days of hospitalization and was not affected by gender and age. MHR was higher in patients with chronic diseases. Patients with high MHR before and after transplantation should be monitored more closely in the perioperative period.Öğe The effect of kinesiophobia on gastrointestinal disorders in patients with lower extremity orthopedic surgery(Frontiers Media Sa, 2025) Gunes, Huseyin; Bulbuloglu, Semra; Saritas, Serdar; Ozdemir, AhmetBackground Postoperative kinesiophobia and gastrointestinal (GI) disorders are common and undesirable conditions following orthopedic surgery. Additionally, managing both conditions is crucial for preventing complications and accelerating recovery. The purpose of this study is to investigate the effects of kinesiophobia on GI disorders after lower extremity orthopedic surgery. Method This study was conducted with a descriptive and cross-sectional design. The sample consisted of a total of n = 299 patients who underwent orthopedic surgery in their lower extremities at the orthopedics and traumatology clinic of a research and training hospital located in Turkey. A personal information form, the Tampa Scale of Kinesiophobia (TSK), and the Gastrointestinal Symptom Rating Scale (GSRS) were used to collect data, and the obtained data were analyzed using descriptive statistics, one-way analysis of variance (ANOVA), paired-samples t-test, and post hoc tests when necessary. Results While 24.4% of the patients were aged 65-74 years, 51.5% were male. The mean total TSK score of the patients was above average (49.36 +/- 8.74), while their mean total GSRS score was below average (31.22 +/- 11.7). In our study, as kinesiophobia increased, the frequency of bowel movements decreased, and kinesiophobia explained 19.9% of the variance in GI disorders (p < 0.05). Conclusions Kinesiophobia is a significant predictor of GI disorders in patients who underwent lower extremity surgery. Returning to normal GI function after surgery is crucial for preventing complications in patients with lower extremity surgery. Uncontrolled kinesiophobia after surgery exacerbates GI disorders. Therefore, early diagnosis and management of both kinesiophobia and GI disorders are necessary for rapid recovery in patients with lower extremity surgery.












