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Öğe Dünyada ve Türkiye'de Covid-19 Aşı Geliştirme Çalışmaları(Manisa Celal Bayar University, 2020) Kazak, Aysun; Hintistan, Sevilay; Önal, BetülDaha önce 2019-nCoV olarak bilinen SARS-CoV-2 (COVID-19) akut bir solunum yolu hastalığıdır ve Çin'den başlayarak tüm dünyaya yayılmıştır. Dünya Sağlık Örgütü (DSÖ) tarafından uluslararası kamu sağlığı acil durumu (30 Ocak 2020) olarak ilan edilen COVID-19'la ilgili genetik ve moleküler çalışmalar ilk günden itibaren başlamış olmasına rağmen, şu ana kadar hala önleyici bir aşı ve kesin bir tedavi yöntemi bulunamamıştır. COVID-19, acil durum olarak ilan edildikten sonra özellikle ilaç ve biyoteknoloji şirketleri ile aşı sektöründeki büyük şirketler ilaç ve aşı üretimi için iş birliği içinde çalışmalarını hızla sürdürmektedir. Bu derlemenin amacı, COVID-19 ile Dünyada ve Türkiye'de COVID-19'u önlemeye yönelik geliştirilen mevcut aşı çalışmaları hakkında bilgi vermek ve bu çalışmaların birlikte analiz edilmesine katkı sunmaktır.Öğe Dünyada ve Türkiye’de COVID-19 Aşı Geliştirme Çalışmaları(2020) Kazak, Aysun; Hintistan, Sevilay; Önal, BetülDaha önce 2019-nCoV olarak bilinen SARS-CoV-2 virüsünün etken olduğu COVID-19 akut bir solunum yolu hastalığıdır. Hastalık, Çin'den başlayarak tüm dünyaya yayılmıştır. Dünya Sağlık Örgütü tarafından uluslararası kamu sağlığı acil durumu (30.01.2020) olarak ilan edilen COVID-19’la ilgili genetik ve moleküler çalışmalar ilk günden itibaren başlamış olmasına rağmen, şu ana kadar hala önleyici bir aşı ve kesin bir tedavi yöntemi bulunamamıştır. COVID-19, acil durum olarak ilan edildikten sonra özellikle ilaç ve biyoteknoloji şirketleri ile aşı sektöründeki büyük şirketler ilaç ve aşı üretimi için iş birliği içinde çalışmalarını hızla sürdürmektedir. Bu derlemenin amacı, COVID-19 ile Dünyada ve Türkiye’de COVID-19’u önlemeye yönelik geliştirilen mevcut aşı çalışmaları hakkında bilgi vermek ve bu çalışmaların birlikte analiz edilmesine katkı sunmaktır.Öğe Evaluation of Symptoms, Laboratory and Thorax Computerized Tomography Findings of COVID-19 Positive Healthcare Professionals: A Retrospective Study(2024) Apaydın, Emine; Akeren, Zahide; Kazak, Aysun; Kuralay, Çıgdem; Hintistan, SevilayObjective: The study was carried out to examine the symptoms and laboratory and thoracic computed tomography findings of COVID-19-positive healthcare professionals in northeastern Turkey. Material and Method: The sample of this descriptive, cross-sectional, and retrospective study consisted of 146 healthcare professionals who had positive COVID-19. Data were collected using electronic data from the hospital information management system and the personal health records of healthcare professionals. Results: 50.6% of COVID-19-positive healthcare professionals were symptomatic, 49.4% were asymptomatic, 52.7% of nurses, midwives, and health officers, and those who were symptomatic experienced the most cough, muscle-joint pain, and fatigue. Healthcare workers had a high leukocyte, neutrophil, lymphocyte, platelet mean, C reactive protein, and D-dimer, and 24.1% had COVID-19-compatible thorax computed tomography. Symptomatic healthcare professionals had a lower median of leukocyte and a higher median of C reactive protein and procalcitonin compared to asymptomatic healthcare professionals. Healthcare professionals with COVID-19 compatible thorax computed tomography had a lower leukocyte, median, and platelet mean, lower high C reactive protein median, and higher D-dimer median. Conclusion: The study found that half of the healthcare professionals are symptomatic, and leukocyte, neutrophil, lymphocyte, C reactive protein, and platelet values affect the development of COVID-19-compatible thoracic computed tomography. The results can be used as a knowledge base for research and by health workers and institutional authorities to implement methods to improve prevention levels.Öğe Factor Affecting Fear, Anxiety and Depression During COVID-19 in Turkey: A Cross- Sectional Study(Marmara Üniversitesi, 2022) Kocak, Seda; Kazak, Aysun; Karakullukçu, SerdarObjective: The aim of this study was to research levels of fear, anxiety and depression related with the COVID-19 outbreak and the potential risk factors contributing these facts within the population of Turkey. Methods: 377 people participated in this study. This study conducted from September to the end of December 2020. An online survey was performed by using the Individual Information Form, The Fear of COVID-19 Scale (7-35 points) and Hospital Anxiety and Depression (HAD) Scale; HAD-A (0-3 points, ?10), HAD-D (0-3 points, ?7). Results: When Hospital Anxiety and Depression Scale are examined, the anxiety scores of 15.9% (> 10, n = 60) and depression scores of 34.2% (> 7, n = 129) of the participants are higher than the cut-off points. HAD-A, HAD-D and COVID-Fear data were positively significantly correlated with each other (p <0.001). In regression analysis, females, those with a relative who has at least one chronic illness, those with mental disorders, and those receiving psychological support were determined as risk factors. Conclusion: Interrelationships of mental wellbeing, and health status changing at an individual basis must be taken into consideration while evaluating psychological effects of COVID-19.Öğe The Effect of COVID-19 Pandemic on the Intolerance of Uncertainty of Students Studying in Health Departments(Duzce University, 2022) Önal, Betül; Kazak, Aysun; Karakullukçu, Serdar; Önal, ErsinAim: The study examines to determine the effect of COVID-19 pandemic on uncertainty and intolerance of students studying in health programs. Material and Methods: The population of the research, which is planned as a descriptive, is consisted of second-year students in the department of health studying at the regional vocational school of the two state universities in the Black Sea region and 807 students who have agreed to participate in the study sample. In the statistical analysis of data, the dual comparison of the number, percentage, average is performed with Student T test and Ki Square test. Results: It has been determined that 76.6% of the students participating in the study are women, 70.8% of them have a moderate-income level, 47% of them live in the city center. While 95.2% of the students took social isolation measures, 18.3% of them or their relatives were quarantined. When the mental health change of the students were questioned during the pandemic period, it was determined that 53.7%of them got worse and 63.2% of them received psychosocial healthcare. When the data of the students regarding COVID-19 and the scores obtained from the scale of intolerance of uncertainty were compared, the scale scores were found to be statistically significant in those who considered mental health change as bad, quarantined, psychosocial healthcare received (p<0.05). Conclusion: During the pandemic period, students are highly socially isolated, pandemic affected students psychology in a negative way. The future professionals of our healthcare system, need to raise awareness for education based on psychosocial health through sensitivity programs as a part of the standard healthcare education.
