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Öğe Anatomy, trichome micromorphology and phytochemical profile of Stachys rizeensis R.Bhattacharjee from Turkey(Elsevier, 2022) Gercek, Yusuf Can; Sahin, Aydan Acar; Bayram, Nesrin Ecem; Celik, Saffet; Sefali, Abdurrahman; Gidik, Betul; Oz, Gul CevahirIn recent years, the popularity of natural products and natural product formulations has increased due to their beneficial effects on health. As a part of this trend, Lamiaceae family members have attracted attention due to their rich bioactive properties. Although the Stachys rizeensis R.Bhattacharjee plant is an endemic plant species in Turkey, no studies focus on its characterization. Hence, the present study aims to demonstrate the anatomical, morphological and phytochemical characterization of S. rizeensis in Turkey. In the first stage of the study, anatomical and trichome morphological characterization was performed to contribute to the taxonomic definition of S. rizeensis was found to be anatomically different from some other previously studied Stachys sp. by showing lacunar collenchyma type, uncertain cambium at the corners, two or three rows of endodermis in certain areas in the stem and two rows of palisade parenchyma, capitate and peltate glandular trichomes in the leaf. In the second stage, the phenolic profile, total phenolic/flavonoid content and antioxidant activity of the plant extracts prepared using solvents with different polarities (ethanol, methanol, water, ethyl acetate and hexane) were tested to determine the phytochemical content of the plant. The phytochem-ical analysis supported by chemometric analysis (PCA and HCA) revealed that methanol was the most efficient organic solvent for the extraction of the phytochemical compounds of the plant. Additionally, it was observed that chlorogenic acid (1842.40-217,086.19 mg/kg), verbascoside (2591.43-204,429.81 mg/kg), luteolin (3579.56-88,636.14 mg/kg) and kaempferol (9706.30-50,340.93 mg/kg) compounds were present at maximum levels in this plant, in which 31 different phenolic compounds were scanned using LC-MS/MS. In addition, results obtained from the phytochemical analysis revealed that S. rizeensis is a valuable plant that can be used for medical protection/treatment and that it could also have a variety of culinary applica-tions. The present study served as the first original report regarding the chemical profile and anatomical characteristics of S. rizeensis (Lamiaceae) from Turkey. (C) 2022 SAAB. Published by Elsevier B.V. All rights reserved.Öğe Androsace artvinensis sp. nov. (Primulaceae): A new species from northeastern Anatolia, Turkey(Magnolia Press, 2022) Sefali, Abdurrahman; Yapar, YakupAndrosace artvinensis (Primulaceae) from Artvin province (northeastern Anatolia) has been described as a new species to science. The new species is morphologically similar to A. armeniaca var. macrantha but differs from it by several morphological characters, such as bracts shape, calyx (calyx length and lobes), corolla (corolla length, lobes, and indumentum), hairs, leaves, pollen features, and habitat preference. Diagnostic morphological characteristics, a full description, and a distribution map are provided.Öğe Androsace azizsancarii sp. nov. (Primulaceae): a new species from northeastern Anatolia, Turkey(Wiley, 2021) Sefali, AbdurrahmanAndrosace azizsancarii (Primulaceae) is described and illustrated as a new species from Bayburt Province in northeastern Anatolia, Turkey. Diagnostic morphological characteristics, a full description and a distribution map are provided. The new species is morphologically closest to Androsace albana, A. multiscapa and A. villosa, but it is easily distinguished from these species by indumentum, leaf, flower and seed characters.Öğe Bellevalia bayburtensis (Asparagaceae): a new species from northeastern Anatolia, Turkey(Magnolia Press, 2020) Yildirim, Hasan; Sefali, AbdurrahmanBellevalia bayburtensis (Asparagaceae) is described and illustrated as a new species from Bayburt Province in northeastern Anatolia, Turkey. Diagnostic morphological characters, a full description, detailed illustrations, and a distribution map are provided. It is morphologically similar to B. rixii and B. paradoxa, but clearly differs from these species by the leaf shape, the bud and flower colour.Öğe Biological activity of Psephellus appendicigerus as a natural agent(Taylor & Francis Ltd, 2021) Acet, Tuba; Ozcan, Kadriye; Sefali, AbdurrahmanPsephellus appendicigerus, is a plant endemic to Turkey, belonging to the Asteraceae family, which is traditionally used in folk medicine in Turkey. The aim of this study is to reveal for the first time the biological activities of this plant and evaluate its potential use as a natural product. For this reason, different extracts (ethanol, methanol, ethyl acetate, and hexane) of the plant's aerial parts were used in determining the antioxidant (2,20-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid and 1,1-diphenyl-2-picrylhydrazyl assays), antimicrobial (disc diffusion and microdilution methods), and enzyme inhibition activity (calorimetric methods) related to diabetes (alpha-amylase and alpha-glucosidase). Moreover, the phenolic constituents were analysed by high performance liquid chromatography. Methanol extract of the plant exhibited significant biological activity compared to other extracts. This extract had the highest amount of chlorogenic acid as phenolic compound. In addition, all extracts showed inhibition against at least one test microorganism. According to the results, P. appendicigerus has the potential to be used as a natural antioxidant, antimicrobial and enzyme inhibitor.Öğe Chemical composition of essential oils and comparative analysis of enzyme inhibitory, antioxidant and antimicrobial activities in essential oils of endemic Gelasia sericea (Aucher ex DC.) Zaika, Sukhor. & N. Kilian(Taylor & Francis Ltd, 2025) Fidan, Muhammed Said; Baltaci, Cemalettin; Akmese, Osman; Sefali, Abdurrahman; Aygul, Imdat; Oz, MehmetIn this study, essential oil from the aerial parts of Gelasia sericea (Aucher ex DC.) Zaika, Sukhor. & N. Kilian was extracted via hydrodistillation using a Clevenger apparatus. GC-MS/FID analysis determined aldehydes (28.31%) as the dominant group, with eucalyptol (8.71%) as the main constituent. Antioxidant activities were exhibited using DPPH, ABTS, and FRAP assays, with the essential oil demonstrating relatively higher antioxidant properties. The essential oil also showed higher levels of bioactive components, including total antioxidant capacity (160.26 mg AA eq./100 mL), total phenolic content (21.57 mg GA eq./100 mL), and total flavonoid content (14.85 mg QE eq./100 mL). While G. sericea essential oil demonstrated some antioxidant activity, it was significantly lower compared to the reference standard ascorbic acid (AA). The antimicrobial results showed relatively higher antimicrobial activity compared to most bacterial and fungal strains, as evidenced by lower MIC and MBC values and larger inhibition zones. Nevertheless, chloramphenicol (CH) and nalidixic acid (NA) continually showed superior antimicrobial efficacy, with the lowest MIC and MBC values and the largest inhibition zones. The essential oil also demonstrated potent enzyme inhibitory activity, especially against CA-II, AChE, and BChE, with the lowest IC50 value observed for CA-II, highlighting its potential as a potent enzyme inhibitor. However, the essential oil exhibited comparatively greater inhibition against AChE, BChE and alpha-amylase but was less effective overall. These findings suggest that the G. sericea essential oil has important antioxidant potential and enzyme inhibitory activity, while the essential oil shows varying efficacy across different enzymes.Öğe Chemical Profiling and Biological Activities of Methanol Extracts and Essential Oils from Ferulago platycarpa Boiss. & Balansa (Endemic): Enzyme Inhibition, Antioxidant, and Antimicrobial Properties(North Carolina State Univ Dept Wood & Paper Sci, 2026) Aygul, Imdat; Oz, Mehmet; Fidan, Muhammed Said; Akmee, Cemalettin Baltaci Osman; Akmese, Osman; Sefali, AbdurrahmanThis study aimed to evaluate the phytochemical composition and biological activities of Ferulago platycarpa methanol extract (ME) and essential oil (EO). The EO was obtained via hydrodistillation and analyzed by GC-MS, revealing sesquiterpene hydrocarbons as the dominant class, with caryophyllene (65.8%) and a-pinene (9.65%) as the major constituents. The methanol extract was subjected to LC-MS/MS analysis, which identified eleven phenolic compounds, with chlorogenic acid as the most abundant. The extract showed significantly higher total phenolic (1196.22 +/- 11.64 mg GAE/100g) and antioxidant (1870.00 +/- 17.69 mg QEE/100g) contents compared to the ME. In vitro enzyme inhibition assays demonstrated that the methanol extract exhibited potent inhibitory activity against carbonic IC50=110 mu g/mL), and butyrylcholinesterase (BChE, IC50=390 mu g/mL). In contrast, the EO showed higher inhibition against a-amylase (IC50=5920 +/- 10.45 mu g/mL) and BChE (IC50=1.32 +/- 0.65 mu g/mL), while its aglucosidase showed no inhibition. Antioxidant assays indicated superior activity for the methanol extract compared to the EO. Furthermore, antimicrobial testing revealed that the EO demonstrated broader and more effective antimicrobial action, exhibiting lower MIC and MBC values against several bacterial and fungal strains. Collectively, these results highlight F. platycarpa as a valuable source of bioactive compounds with promising applications in antidiabetic, neuroprotective, antioxidant, and antimicrobial therapies.Öğe Contributions on the southern distribution of Vespertilio murinus Linnaeus, 1758 (Chiroptera: Vespertilionidae) from Turkiye(Tubitak Scientific & Technological Research Council Turkey, 2022) Karatas, Ahmet; Bulut, Safak; Sefali, Abdurrahman; Toprak, Ferhat; Sahin, Mehmet Kursat; Ozkurt, Sakir OnderVespertilio murinus Linnaeus, 1758, has a wide distribution from France to Japan, and from Iran in the south to Scandinavia and Russia in the north. The only records of the parti-coloured bat, Vespertilio murinus known from Turkey so far were based on subfossils, remains from owl pellets, and ultrasound recordings. We present the first records of live individuals from two Turkish provinces, Ardahan and Bayburt. Additionally, based on echolocation call records, its known distribution in the Anatolian Peninsula was proved to be wider. The global distribution of the species has been mapped by using ecological niche modelling. The results revealed that its distribution is highly influenced by precipitation dynamics. Although no cases of domestic cat predation on bats have previously been documented in Turkey, this paper also provides the first case study of V. murinus predated by a domestic cat in Ardahan, in November 2003.Öğe DETERMINATION OF ANTIOXIDANT, ANTIMICROBIAL ACTIVITIES, PHENOLIC COMPOUNDS OF WILD ROSA L. SPECIES BAYBURT, TURKEY(Parlar Scientific Publications (P S P), 2019) Gidik, Betul; Akar, Zeynep; Can, Zehra; Sefali, Abdurrahman; Erturk, OmerFive different rosehip (Rosa L.) species including, Rosa canina, Rosa iberica Stev, Rosa villosa, Rosa beggeriana Schrenk and same kind of but different location Rosa spinosissima grown in Bayburt from Turkey are studied. The wild species of Rosa L. were collected from Rocks and Steps, Field and garden borders. Morphological parameters were measured as fruit and seed weights and fruit and seed size. Ten fruits were chosen randomly for the measurement and take the average of them to determine the weights and size. In our study was determined antioxidant activity, antimicrobial activity and phenolic compounds. As antioxidant activity; total phenolic total flavonoid, condense tannin contents, CUPRAC, FRAP, ABTS. Nineteen standard of phenolic compositions of fruits and seeds were determined. Antioxidant, antimicrobial activities of the extracts were found high levels in rose hip species fruit than seed. Catechin, rutin protocatequic acid and CAPE were principal for all rose hip species fruit but, was not deteceted CAPE Kop Mountain, Yukari Kop Village Rosa spinosissima species. This suggests that the difference in location affects the phenolic content. Pearson Correlation analyze has done with the morphological parameters, GPS data, antioxidant activity and phenolic compounds by using the SPSS software programme version 25.0.Öğe Enzyme inhibitory, antioxidant, antimicrobial activities, and phenolic profiles of the methanol extract of Gelasia sericea an endemic species(Univ Agr Sci & Veterinary Med Cluj-Napoca, 2025) Aygul, Imdat; Akmese, Osman; Sefali, Abdurrahman; Baltaci, Cemalettin; Oz, Mehmet; Fidan, Muhammed SaidThis study aimed to investigate, for the first time, the phytochemical composition, antioxidant, antimicrobial, and enzyme inhibitory properties of the methanolic extract of Gelasia sericea (Aucher ex DC.) Zaika, Sukhor. & N.Kilian. The extract demonstrated a moderate yield (6.55 g/100 g dry plant material) and was found to be rich in phenolic acids, particularly ferulic acid (17182.97 mu g g-1), followed by caffeic acid, protocatechuic acid, and p-coumaric acid. Antioxidant analyses revealed high total phenolic (388.86 mg GA eq./100 g), total flavonoid (74.03 mg QE eq./100 g), and total antioxidant capacity (503.33 mg AA eq./100 g). The extract exhibited remarkable ABTS radical scavenging activity (95.99%, IC50 = 37.59 mg ml-1) and considerable ferric-ion reducing power (974.78 mg FeSO4 eq./100 g). Antimicrobial assays indicated moderate inhibitory effects, with stronger activity against Gram-positive bacteria (Staphylococcus aureus, Enterococcus faecalis) and the yeast Candida albicans, whereas Gram-negative bacteria were less susceptible. The extract's MIC values ranged between 0.20-3.25 mg ml-1, and MLC values between 0.41-6.50 mg ml-1, which were higher than those of standard antibiotics. Enzyme inhibition assays revealed moderate activity against carbonic anhydrase II (IC50 = 0.0136 mu g ml-1) and weak inhibition of cholinesterases and alpha-glucosidase, while alpha-amylase inhibition was relatively more pronounced (IC50 = 13350.00 mu g ml-1). Overall, these findings highlight G. sericea as a valuable natural source of phenolic acids and antioxidants, with promising potential for applications in functional foods, nutraceuticals, and phytopharmaceuticals. However, the relatively limited antimicrobial and enzyme inhibitory activities suggest the need for further studies on bioavailability, in vivo efficacy, and compound isolation to optimize its practical applications.Öğe Fruit and seed macro- and micromorphologies of the genus Matthiola (Brassicaceae) in Turkey and their taxonomic value(Tubitak Scientific & Technological Research Council Turkey, 2019) Kaya, Ayla; Unal, Murat; Sefali, Abdurrahman; Martin, EsraMacro- and micromorphological features of fruit and seeds belonging to 12 taxa genera of Matthiola W.T. Aiton were studied via stereomicroscope and scanning electron microscope. In macromorphological studies, the following variables were investigated: the shape, size, and color of fruit and seeds; the length of fruiting pedicel; the structure of the median vein; stigma (horns); and trichome properties and density in fruit. In micromorphological studies, the presence or absence of seed wings, seed coat pattern in disc and wing, and epidermal cell shape in disc and wing were determined. According to our findings, all characters of fruit and seeds are extremely variable and can be used as criteria to distinguish species of the genus.Öğe Pastinaca vanensis (Apiaceae), a new species from Turkey(Magnolia Press, 2022) Demir, Ibrahim; Sefali, Abdurrahman; Yapar, YakupPastinaca vanensis is described as a new species from the Ba??kale district (Van-Turkey). Its diagnostic characteristics are discussed, and taxonomic comments are presented. P. vanensis is related to Pastinaca zozimoides but differs from this spe-cies in indumentum, petal color, and mericarp features. Data on ecology and the conservation status of the new species are also presented. A distribution map of the new and related species is provided.Öğe Phytochemical analysis and biological evaluation of essential oils and extracts from Heracleum pastinacifolium subsp. incanum (Boiss. & A.Huet) PHDavis, an endemic plant from Turkey(Taylor & Francis Ltd, 2024) Yuca, Hafize; Sefali, Abdurrahman; Aydin, Bilge; Karadayi, Mehmet; Gulsahin, Yusuf; Yazici, Aysenur; Karakaya, SongulEssential oil content of and phenolic compounds flower-fruit, root, and aerial parts of Heracleum pastinacifolium subsp. incanum were analysed by GC/MS and LC/MS methods, respectively. Antidiabetic, anticholinesterase, and antioxidant activities of flower-fruit, root, aerial parts methanol extracts were evaluated. Apiole (35.0%), myristicine (72.2%), and myristicine (15.1%) were found as major compounds of fruit-flower mixture, root, aerial part essential oils, respectively. Hesperidin was found the highest amount in aerial part and flower-fruit extracts with 8904.2621 ng/mL and 11558.3634 ng/mL values, respectively. Fruit-flower extract showed the highest activity against alpha-glucosidase (24%). Root extract demonstrating the highest activity (18%) against AChE enzyme. Flowers-fruits mixture methanol extract had a higher % inhibition value on ABTS(+) and DPPH center dot. Flowers-fruits mixture methanol extract was rich in total phenol, total tannin, and protein content. All the extracts were determined as genetoxically safe according to the results of Ames/Salmonella, Escherichia coli WP2 and Allium cepa assays.Öğe Primula longipes subsp. bayburtensis Sefali, Yapar & Demir (Primulaceae): A new taxon from north-eastern Anatolia, Türkiye(Pensoft Publishers, 2025) Sefali, Abdurrahman; Yapar, Yakup; Demir, Ibrahim; Yurtvermez, Bayram; Keser, Ali MuratThe new taxon, Primula longipes subsp. bayburtensis Sefali, Yapar & Demir, subsp. nov. (Primulaceae) is described and illustrated from Bayburt Province, T & uuml;rkiye. It is morphologically assigned to Primula sect. Crystallophlomis based on its long scapes, lanceolate and denticulate leaf with long petiole and hairless habit, fruits longer than calyx and covered by farina on the scape. This new taxon is similar to Primula longipes and P. nivalis subsp. turkestanica; it can also be easily distinguished by its calyx divided ratio, thurm flowers (unwidened corolla tube shape and length) and capsules (length) futures.Öğe A STUDY OF WILD PLANT SPECIES OF BRASSICACEAE FAMILY IN BAYBURT REGION OF TURKEY(Pakistan Botanical Soc, 2019) Gidik, Betul; Gul, Volkan; Sefali, AbdurrahmanThe Brassicaceae (Cruciferae) is one of the most important groups and it has 338 genera and 3709 species around the worldwide. Plant samples of the Brassicaceae family were collected and photographed during the vegetation period of 2017. The plant samples and the photos were taken from their natural habitat between 23 April and 11 August 2017. The locations were determined based on differences in geographical features with variable ecological conditions. 38 genera and 80 species and subspecies were identified from different locations of the study area. Heldreichia bupleurifolia Boiss. subsp. rotundifolia, Aethionema caespitosum, Thlaspi lilacinum, Tchihatchewia isatidea, Bornmuellera cappadocica, Aurinia rupestris subsp. cyclocarpa, Alyssum stylare, Alyssum pseudomouradicum, Alyssum peltarioides Boiss. subsp. peltarioides are endemic taxa for Bayburt.Öğe Three new records for the flora of Turkey: Campanula lyrata subsp. icarica (Campanulaceae), Erysimum aureum (Brassicaceae) and Stachys benthamiana (Lamiaceae)(Magnolia Press, 2022) Ozdol, Tugkan; Guner, Ozal; Sefali, Abdurrahman; Akcicek, Ekrem; Dirmenci, Tuncay; Yildirim, Hasan[Abstract Not Available]
