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    Synthesis, Characterization and Investigation of Antimicrobial Activities of Salts and Complexes Containing 2-Amino-5-Bromopyridine and Dipicolinic Acid
    (Bayburt Üniversitesi, 2025) Yılmaz, Beyza; İlkimen, Halil; Yurt, Elif; Polat, Ayşe; Gülbandılar, Aysel
    The salt {(H2a5Brp)(Hpka), 1} of 2-amino-5-bromopyridine (2a5Brp) and dipicolinic acid (H2pka) and metal complexes of salt (1) {(H2a5Brp)[Fe(pka)2].2H2O (2), (H2a5Brp)2[Co(pka)2].4H2O (3), (H2a5Brp)2[Ni(pka)2].3H2O (4), (H2a5Brp)2[Cu(pka)2].2H2O (5)} were synthesized. Elements analysis, NMR, AAS, IR, UV, molar conductivity magnetic, and susceptibility procedures all showed the structures of 1–5. Spectroscopic investigation showed that every metal compound had an octahedral and ionic structure. All substances were tested for their antimicrobial properties against the following microorganisms: Candida albicans (ATCC 14053) (yeast), Bacillus subtilis, Listeria monocytogenes (ATCC 7644), Pseudomonas aeruginosa (ATCC 27853), Enterococcus faecalis (ATCC 29212), and Staphylococcus aureus (NRRL-B 767) bacteria. Results Of Antimicrobial Activity Were Contrasted With Those Of Ketoconazole, Fluconazole, Vancomycin, Cefepime, Chloramphenicol, and Levofloxacin. The findings of the activity indicated that the highest values were found 3 in C. albicans yeast, all compounds in E. coli bacteria, 1 and 2 in S. aureus bacteria, 2 in L. monocytogenes bacteria, 1 in B. subtilis bacteria, 2a5Brp, 1 and 2 in P. aeruginoa bacteria and all compounds (except 4 and 5) in E. faecalis bacteria.