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    Plasma polymerized linalool (ppLin): An antimicrobial and biocompatible coating [2]
    (TUBITAK, 2019) Çakmak, Kenan; Bayram, Özkan; Solak, Kübra; Kaban, Güzin; Şimşek, Önder; Mavi, Ahmet
    Bacterial infections in medical devices and drug resistance of bacteria can cause chaos in the world due to loss of lives in addition to the cost of device revisions, quarantine, disinfection of infected areas, and patient treatment. Antibacterial coatings of essential oils on medical devices can prevent bacterial attachment and reduce costs. Linalool is an antibacterial constituent of essential oils. Herein, we examine for the first time the fabrication and characterization of radio frequency (RF) plasma polymerized hydrophilic thin films from linalool (ppLin) by varying deposition parameters (RF power and deposition time) and the behavior of ppLin with two bacteria (Escherichia coli and Staphylococcus aureus) commonly related to microbial contamination of medical devices. While a dramatic reduction in E. coli and S. aureus attachment was observed on ppLin films, their hydrophilic surface was also bactericidal to S. aureus. Additionally, ppLin films were shown to be adherent and noncytotoxic to human fibroblast cells. ppLin can be potentially integrated into medical and other clinical devices as a promising low-cost biocompatible antimicrobial coating. © TÜBİTAK
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    Potential bacteriocinogenic lactic acid bacteria from pastırma
    (2021) Güllüce, Medine; Kaya, Mükerrem; Kaban, Güzin; Karadayı, Mehmet; Alaylar, Burak; Kamıloğlu, Aybike; Işık, Ceyda
    Recent researches conducted have focused on the possibility of using bacteriocin produced by lactic acid bacteria both(LAB) as protective cultures and as natural antimicrobial agents in dry cured meat products such as pastırma. In thepresent study, 50 lactic acid bacteria strains, previously isolated from various traditional pastırma samples, were testedfor their antimicrobial potentials. Determination of antagonistic activities against food-borne pathogenic strains (Listeriamonocytogenes, Staphylococcus aureus and Bacillus cereus) were done by using agar-spot and well diffusion assays.Then, active isolates were identified by using 16S rRNA gene sequence analysis. According to the results, 11 of testedLAB were determined with significant bacteriocinogenic potential and these were assigned to as 1 Lactobacillusplantarum, 9 L. plantarum subsp. plantarum and 1 Pediococcus pentosaceus. In conclusion, it was reached that theisolated/identified bacteriocin-producing lactic acid bacteria strains from pastırma samples have a significant potential toprepare pure or crude bacteriocin preparations.
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    Tarhun ve Kişniş Tohumunun Uçucu Yağ Bileşenleri
    (Bayburt University, 2019) Yılmaz, Özlem; Kaban, Güzin; Kaya, Mükerrem
    Araştırmada, Bayburt ilinden temin edilen tarhun (Artemisia dracunculus) ile Erzurum ilinden temin edilen kişniş tohumu (Coriandrum sativum) örneklerinin su distilasyonu ile uçucu yağları elde edilmiştir. Elde edilen yağların uçucu yağ bileşenleri gaz kromatografisi/kütle spektrometrisi(GC/MS) ile belirlenmiştir. Kişniş tohumunda 38, tarhunda ise 48 bileşen tanımlanmıştır. Kişniş tohumu uçucu yağının en önemli bileşeni linalool olarak belirlenmiştir. Bunu sırasıyla ?-terpinen, alfa pinen, geraniol ve D-limonen izlemiştir. Bütanal, pentanal, hekzanal, 2-hekzanal, heptanal, benzaldehit, kopaen, alfa-fellandren ve 3-karen ise oldukça düşük miktarlarda belirlenmiştir. Tarhun uçucu yağında major bileşen olarak estragol belirlenmiş ve bunu sırasıyla metil öjenol, elemisin, isoelemisin, ?-osimen, terpinen-4-ol ve D-limonen izlemiştir.