Association of the enteral nutrition support with mortality, biochemical parameters, and health markers in geriatric patients with COVID-19: A retrospective cohort study

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dc.contributor.authorÖzçelik, Ayşe Özfer
dc.contributor.authorEsgın, Ozge
dc.contributor.authorEthemoğlu, Filiz Banu
dc.contributor.authorÖzyürek, Serkan
dc.contributor.authorAykırı, Hilal
dc.date.accessioned2026-09-01T15:50:26Z
dc.date.available2026-09-01T15:50:26Z
dc.date.issued2026
dc.departmentBayburt Üniversitesi
dc.description.abstractThis study aims to evaluate the association of the enteral nutrition support on mortality, biochemical parameters, and health markers in geriatric patients with COVID-19 treated in intensive care units (ICUs). A retrospective cohort analysis was conducted on 226 patients aged 60 years and older admitted to the COVID-19 adult ICU of Yıldırım Beyazıt University Training and Research Hospital in 2021. Demographics, ICU stay characteristics, biochemical parameters, and nutrition therapy details were collected from hospital records. Patients receiving enteral nutrition were categorized by product type (e.g., diabetic, immunonutrition, glutamine-containing, etc.), and their association on mortality, biochemical markers, and ICU outcomes were evaluated. The mortality rate was 50.4%, with an mean ICU stay of 9.63±6.50 days. Most patients (90.3%) had chronic conditions. Nutrition therapy was administered to 138 patients using various products. Immunonutrition products were associated with improved albumin levels and reduced mortality (p<0.05). Chronic conditions significantly increased mortality risk and ICU stay duration (p<0.05). Multivariate analysis revealed that longer ICU stays and the presence of chronic diseases independently reduced survival probability. Enteral nutrition support, particularly immunonutrition, may benefit geriatric ICU patients with COVID-19 by improving biochemical parameters and reducing mortality risk. Although patients receiving diabetic and glutamine-enriched products have a higher incidence of pressure ulcers, it should be considered that such products are likely to have been used in higher-risk patients.
dc.identifier.doi10.5455/medscience.2025.10.290
dc.identifier.endpage425
dc.identifier.issn2147-0634
dc.identifier.issue1
dc.identifier.startpage413
dc.identifier.trdizinid1391571
dc.identifier.urihttps://doi.org/10.5455/medscience.2025.10.290
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1391571
dc.identifier.urihttps://hdl.handle.net/20.500.12403/8417
dc.identifier.volume15
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofMedicine Science
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TR_20260820
dc.subjectBeslenme ve Diyetetik
dc.subjectAcil Tıp
dc.subjectEnfeksiyon Hastalıkları
dc.titleAssociation of the enteral nutrition support with mortality, biochemical parameters, and health markers in geriatric patients with COVID-19: A retrospective cohort study
dc.typeArticle

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