Investigating the adipokine and cardiac troponin response ın experimental thyroid dysfunction

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dc.contributor.authorBayraktar, Bülent
dc.contributor.authorTekce, Emre
dc.contributor.authorTakma, Çiğdem
dc.contributor.authorBayraktar, Sevil
dc.contributor.authorKilinç, Ayten A.
dc.contributor.authorÜlker, Ufuk
dc.contributor.authorKurtdede, Efe
dc.date.accessioned2024-10-04T18:58:42Z
dc.date.available2024-10-04T18:58:42Z
dc.date.issued2020
dc.departmentBayburt Üniversitesien_US
dc.description.abstractThis study was conducted to investigate adipokine [Apelin and brain-derived neurotrophic factor (BDNF)] and cardiac troponin (cTnI) response that emerged after adding an essential oil mixture (EOM) (Eucalytus glabutus labii, Thymus vulgaris, Cymbopogon nardus, and Syzygium aromaticum) at different rates to the drinking water of broilers in which thyroid dysfunction (hypo-and hyperthyroidism) had been experimentally induced. In the present study, 150 1-day-old Ross-308 male broiler chicks were used. They were divided into five groups, each with 30 animals. The groups were designed to include five subgroups: control (C), hypothyroid, hypothyroid + 250 ppm EOM, hyperthyroid, and hyperthyroid + 250 ppm EOM, with six animals in each group. At the end of the experiment, Apelin, p-BDNF, cTnI, T3, T4, and thyroid-stimulating hormone (TSH) levels were investigated in blood serum samples obtained by cervical dislocation from four randomly selected animals from each subgroup, making 100 animals in total. It was found that EOM administration resulted in a dose-dependent increase in p-BDNF and apelin levels, and a decrease in T4 levels in the experimentally induced hypo-and hyper-thyroidism groups, but did not affect T3 and cTnI levels. Conversely, an increase in TSH level was observed in the hypothyroidism groups, whereas a decrease was observed in groups with hyperthyroidism. This study is the first to examine adipokine (Apelin and BDNF) and cTnI response to EOM administration in thyroid dysfunction. © 2020, University of Zagreb, Facultty of Veterinary Medicine. All rights reserved.en_US
dc.identifier.doi10.24099/VET.ARHIV.0783
dc.identifier.endpage296en_US
dc.identifier.issn0372-5480
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85088522481en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage289en_US
dc.identifier.urihttps://doi.org/10.24099/VET.ARHIV.0783
dc.identifier.urihttp://hdl.handle.net/20.500.12403/3990
dc.identifier.volume90en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherUniversity of Zagreb, Facultty of Veterinary Medicineen_US
dc.relation.ispartofVeterinarski Arhiven_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectApelinen_US
dc.subjectBrain-derived neurotrophic factoren_US
dc.subjectBroiler chicksen_US
dc.subjectCardiac troponinen_US
dc.subjectEssential oil mixtureen_US
dc.subjectThyroid dysfunctionen_US
dc.titleInvestigating the adipokine and cardiac troponin response ın experimental thyroid dysfunctionen_US
dc.title.alternativeOdgovor adipokina i sr?anog troponina na eksperimentalno izazvanu disfunkciju štitne ?lijezde brojleraen_US
dc.typeArticleen_US

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