Silver nanoparticle synthesis by biogenic reduction method and investigation of antimicrobial, antibiofilm, anticancer activities

Basit Öğe Kaydı
dc.contributor.authorKarakaya, Funda
dc.contributor.authorBülbül, Ali Savaş
dc.contributor.authorBekmezci, Muhammed
dc.contributor.authorŞen, Fatih
dc.date.accessioned2024-10-04T19:07:34Z
dc.date.available2024-10-04T19:07:34Z
dc.date.issued2023
dc.departmentBayburt Üniversitesien_US
dc.description.abstractIn this study, R. aculeatus plant extract and biogenically formed AgNPs were investigated for their potential antibacterial, antibiofilm and anticancer abilities. AgNPs were characterised using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) and UV-vis spectroscopy (UV-VIS). According to the Debye Scherrer formula, the particle size was found to be 32.56 nm. Disc diffusion and microdilution methods were used to investigate the antibacterial activity. In the disc diffusion study, the best results were obtained from the extract and AgNP. In the tests using plant extracts, Staphylococcus aureus ATCC 25923 showed the lowest antibiofilm activity, while Bacillus subtilis and Enterobacter aerogenes ATCC 13048 showed the highest activity. Salmonella infantis was most affected by AgNP, while Escherichia coli CFAI ATCC 25922 was least affected. Biogenically synthesised AgNPs were also investigated in cytotoxic activity studies. It was found to have the lowest concentration value on MCF-7 and HUVEC cell lines at the determined concentrations. The extract did not have any cytotoxic effect on MCF-7 cell line. HUVEC cell line showed the lowest cytotoxic activity of $10^{-3}$ g/mL. The antibacterial, antibiofilm and anticancer properties of R. aculeatus plant extract and biogenically produced AgNPs have been the subject of an important study. Furthermore, the comparison of the effects of plant extract and AgNPs on breast cancer cell lines and healthy cell lines provides a rich scientific material.en_US
dc.identifier.doi10.59313/jsr-a.1277894
dc.identifier.endpage15en_US
dc.identifier.issn2687-6167
dc.identifier.issue55en_US
dc.identifier.startpage1en_US
dc.identifier.trdizinid1223368en_US
dc.identifier.urihttps://doi.org/10.59313/jsr-a.1277894
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1223368
dc.identifier.urihttp://hdl.handle.net/20.500.12403/4699
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofJournal of scientific reports-A (Online)en_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntimicrobial Activityen_US
dc.subjectAntibiofilm Activityen_US
dc.subjectAnticancer Activityen_US
dc.subjectBiogenic Agenten_US
dc.titleSilver nanoparticle synthesis by biogenic reduction method and investigation of antimicrobial, antibiofilm, anticancer activitiesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu