Phytochemical Analysis and Determination of Antioxidative, Antimicrobial And In Vitro Cytotoxic Properties of Black Rosehip (Rosa Pimpinellifolia L.) Fruits Growing in The Northeast of Türkiye

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dc.contributor.authorKıcık, Büşra
dc.contributor.authorKızıl, Hamit Emre
dc.contributor.authorBayram, Sinan
dc.date.accessioned2026-02-28T11:58:22Z
dc.date.available2026-02-28T11:58:22Z
dc.date.issued2024
dc.departmentBayburt Üniversitesi
dc.description.abstractThe aim of this study was to determine the phenolic content of Rosa pimpinellifolia (L.) fruit extract and antibacterial, antioxidant activity and show the cytotoxic effects of different concentrations of Rosa pimpinellifolia L. fruit extract obtained by ultrasonic assisted method on MCF-7 cell line by WST-8 assay. Antibacterial effects analyzed by disk diffusion method and determined that there was no antibacterial effect in 500 ?g/mL Rosa pimpinellifolia L. fruit extract dose. In addition, the total phenolic content was determined by the Folin-Ciocalteu method and found that total phenolic content is 37.5±0.2 mg GA/g. Antioxidant activity value was determined as 32.06±1.1 mg TE/g by ABTS method and 23.47±1.6 mg TE/g by DPPH method. The highest cytotoxic effect of Rosa pimpinellifolia L. fruit extract was determined in dose of 40 ?g/mL on MCF-7 cell.
dc.identifier.doi10.46810/tdfd.1455825
dc.identifier.endpage28
dc.identifier.issn2149-6366
dc.identifier.issue4
dc.identifier.startpage23
dc.identifier.trdizinid1294445
dc.identifier.urihttps://doi.org/10.46810/tdfd.1455825
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1294445
dc.identifier.urihttps://hdl.handle.net/20.500.12403/5513
dc.identifier.volume13
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTürk Doğa ve Fen Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TR-Dizin_20260218
dc.subjectMCF-7
dc.subjectantioxidant
dc.subjectantibacterial
dc.subjectcytotoxic
dc.subjectRosa pimpinellifolia (L.)
dc.titlePhytochemical Analysis and Determination of Antioxidative, Antimicrobial And In Vitro Cytotoxic Properties of Black Rosehip (Rosa Pimpinellifolia L.) Fruits Growing in The Northeast of Türkiye
dc.typeArticle

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