DETERMINATION OF IN -VITRO ANTIOXIDANT, ANTI-UREASE, ANTI-HYALURONIDASE ACTIVITIES BY PHENOLIC RICH BEE PRODUCTS FROM DIFFERENT REGION OF TURKEY

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dc.contributor.authorCan, Zehra
dc.date.accessioned2024-10-04T18:49:26Z
dc.date.available2024-10-04T18:49:26Z
dc.date.issued2018
dc.departmentBayburt Üniversitesien_US
dc.description.abstractIn this study, enzyme inhibition of urease and hyaluronidase are clinically important functions were examined by different authenticity bee products. Different floral honey, pollen and propolis samples were analyzed in terms of total phenolic compounds (TPC), total flavonoid contents (TFC), ferric reducing antioxidant capacity (FRAP), cupric reducing antioxidant capacity (CUPRAC), and 2,2-diphenyl-l-picryhydrazyl (DPPH) free radical scavenging activities as antioxidant determinants. For the determination of the phenolic composition of the products, RP-UV-HPLC was used. TPC of the honey, pollen and propolis samples were ranged from 17 to 95 and 770 to 989 mg of gallic acid (GAE)/100g, 135-258 mg of GAE/g, and TFC was 1 to 10 mgQE/100g, and 78 to 99 mgQE/100 g, and 9 to 10 mg of QE/g, respectively. Among the bee products, propolis samples were showed the highest phenolic componds, that contained different quantity of protocatequic acid, catechin, caffeic acid, p-coumaric acid, p- hydroxybenzoic acid, ferulic acid and rutin. The urease inhibition vales (IC50) were changed from 7.02 to 33.25 mg/mL, 5.00 to 8.78 and 0.16 to 1.98 mg/mL in the honey, pollen and propolis samples, respectively. The hyaluronidase inhibition values (IC50) were changed from 0.02 to 0.46 g/mL, 0.02 to 0.26 g/mL and 3.26 to 9.21 mu g/mL in the honey, pollen and propolis samples, respectively. Honey, pollen and propolis have a significant inhibition on the enzymes, the inhibition may be due to secondary metabolites of phenolic compounds and the mechanism of the inhibition should be studied in detailed.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK) [114Z370]en_US
dc.description.sponsorshipWe are grateful to the Scientific and Technological Research Council of Turkey (TUBITAK) for its support for the study through its contributions to project No. 114Z370.en_US
dc.identifier.endpage6866en_US
dc.identifier.issn1018-4619
dc.identifier.issn1610-2304
dc.identifier.issue10en_US
dc.identifier.startpage6858en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12403/3140
dc.identifier.volume27en_US
dc.identifier.wosWOS:000449141700048en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherParlar Scientific Publications (P S P)en_US
dc.relation.ispartofFresenius Environmental Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBee productsen_US
dc.subjectureaseen_US
dc.subjecthyaluronidaseen_US
dc.subjectenzyme inhibitionen_US
dc.subjectantioxidanten_US
dc.titleDETERMINATION OF IN -VITRO ANTIOXIDANT, ANTI-UREASE, ANTI-HYALURONIDASE ACTIVITIES BY PHENOLIC RICH BEE PRODUCTS FROM DIFFERENT REGION OF TURKEYen_US
dc.typeArticleen_US

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