DETERMINATION OF ANTIGENOTOXIC EFFECTS OF FOUR LICHEN SPECIES BY USING HUMAN LYMPHOCYTES

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dc.authoridAlpsoy, Lokman/0000-0002-3524-9485
dc.authoridKIZIL, Hamit Emre/0000-0001-6193-3734
dc.authoridAgar, Guleray/0000-0002-8445-5082
dc.contributor.authorAnar, Mustafa
dc.contributor.authorAslan, Ali
dc.contributor.authorCeker, Selcuk
dc.contributor.authorKizil, Hamit Emre
dc.contributor.authorAlpsoy, Lokman
dc.contributor.authorAgar, Guleray
dc.date.accessioned2024-10-04T18:49:26Z
dc.date.available2024-10-04T18:49:26Z
dc.date.issued2015
dc.departmentBayburt Üniversitesien_US
dc.description.abstractIn this study, the geno-toxic and antigeno-toxic properties of the total extracts of four lichen species were investigated by using human lymphocytes. We obtained total extracts from R. farinacea, X parietina, U articulata and U. filipendula lichen species. The results of our studies showed that 5 mu M concentrations of AFB(1) changed the frequencies of micronucleus (MN) and malondialdehyde (MDA) levels, as well as superoxide dismutase (SOD), glutathione (GSH) and glutathione peroxidase (GPx) activities. When 5, 10 and 20 mu g/ml concentrations of total extract were added to AFB(1), the frequencies of MN and MDA levels were decreased, and SOD, GSH and GPx levels were increased. Consequently, our findings show that four lichen total extracts have strong antigenotoxic properties against aflatoxin B-1.en_US
dc.description.sponsorshipAtaturk University [2011/219]en_US
dc.description.sponsorshipThis study was supported by a grant from the Research Funds appropriated to Ataturk University (Project number: 2011/219).en_US
dc.identifier.endpage4256en_US
dc.identifier.issn1018-4619
dc.identifier.issn1610-2304
dc.identifier.issue12en_US
dc.identifier.startpage4251en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12403/3138
dc.identifier.volume24en_US
dc.identifier.wosWOS:000367699000004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherParlar Scientific Publications (P S P)en_US
dc.relation.ispartofFresenius Environmental Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRamalina farinacea (L.) Ach.en_US
dc.subjectXanthoria parietina (L.) Th. Fr.en_US
dc.subjectUsnea articulataen_US
dc.subjectUsnea filipendulaen_US
dc.subjectAFB(1)en_US
dc.subjectantimutagenicen_US
dc.subjectantigenotoxicen_US
dc.titleDETERMINATION OF ANTIGENOTOXIC EFFECTS OF FOUR LICHEN SPECIES BY USING HUMAN LYMPHOCYTESen_US
dc.typeArticleen_US

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