Determination of in-vitro antioxidant, anti-urease, anti-hyaluronidase activities by phenolic rich bee products from different region of Turkey

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dc.authorid55201589100
dc.contributor.authorCan Z.
dc.date.accessioned20.04.201910:49:12
dc.date.accessioned2019-04-20T21:43:08Z
dc.date.available20.04.201910:49:12
dc.date.available2019-04-20T21:43:08Z
dc.date.issued2018
dc.departmentBayburt Üniversitesien_US
dc.description.abstractIn this study, enzyme inhibition of urease and hyaluronidase are clinically important functions were examined by different authenticity bee products. Different floral honey, pollen and propolis samples were analyzed in terms of total phenolic compounds (TPC), total flavonoid contents (TFC), ferric reducing antioxidant capacity (FRAP), cupric reducing antioxidant capacity (CUPRAC), and 2,2-diphenyl-1-picryhydrazyl (DPPH) free radical scavenging activities as antioxidant determinants. For the determination of the phenolic composition of the products, RP-UV-HPLC was used. TPC of the honey, pollen and propolis samples were ranged from 17 to 95 and 770 to 989 mg of gallic acid (GAE)/100g, 135-258 mg of GAE/g, and TFC was 1 to 10 mgQE/100g, and 78 to 99 mgQE/100 g, and 9 to 10 mg of QE/g, respectively. Among the bee products, propolis samples were showed the highest phenolic componds, that contained different quantity of protocatequic acid, catechin, caffeic acid, p-coumaric acid, p-hydroxybenzoic acid, ferulic acid and rutin. The urease inhibition vales (IC50) were changed from 7.02 to 33.25 mg/mL, 5.00 to 8.78 and 0.16 to 1.98 mg/mL in the honey, pollen and propolis samples, respectively. The hyaluronidase inhibition values (IC50) were changed from 0.02 to 0.46 g/mL, 0.02 to 0.26 g/mL and 3.26 to 9.21 ?g/mL in the honey, pollen and propolis samples, respectively. Honey, pollen and propolis have a significant inhibition on the enzymes, the inhibition may be due to secondary metabolites of phenolic compounds and the mechanism of the inhibition should be studied in detailed. © by PSP.en_US
dc.identifier.endpage6866
dc.identifier.issn1018-4619
dc.identifier.issue10
dc.identifier.scopus2-s2.0-85055261438en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage6858
dc.identifier.urihttps://hdl.handle.net/20.500.12403/413
dc.identifier.volume27
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherParlar Scientific Publications
dc.relation.ispartofFresenius Environmental Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidant
dc.subjectBee products
dc.subjectEnzyme inhibition
dc.subjectHyaluronidase
dc.subjectUrease
dc.subjectantioxidant
dc.subjectchemical compound
dc.subjectconcentration (composition)
dc.subjectenzyme
dc.subjectenzyme activity
dc.subjectfree radical
dc.subjectinhibition
dc.subjectphenolic compound
dc.subjectpollen
dc.subjectsecondary metabolite
dc.subjectTurkey
dc.subjectApoidea
dc.subjectAntioxidant
dc.subjectBee products
dc.subjectEnzyme inhibition
dc.subjectHyaluronidase
dc.subjectUrease
dc.subjectantioxidant
dc.subjectchemical compound
dc.subjectconcentration (composition)
dc.subjectenzyme
dc.subjectenzyme activity
dc.subjectfree radical
dc.subjectinhibition
dc.subjectphenolic compound
dc.subjectpollen
dc.subjectsecondary metabolite
dc.subjectTurkey
dc.subjectApoidea
dc.titleDetermination of in-vitro antioxidant, anti-urease, anti-hyaluronidase activities by phenolic rich bee products from different region of Turkeyen_US
dc.typeArticleen_US

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