Bioinspired Sternal Implant Design for Generic Anatomical Reconstruction: An In Silico Framework for Material Selection and Biomechanical Validation

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dc.contributor.authorKutbay, Isil
dc.contributor.authorGerdan, Zeynep
dc.contributor.authorColak, Murat
dc.contributor.authorTabak, Yasemin
dc.contributor.authorSensoy, Abdullah Tahir
dc.date.accessioned2026-09-01T15:52:34Z
dc.date.available2026-09-01T15:52:34Z
dc.date.issued2026
dc.departmentBayburt Üniversitesi
dc.description.abstractThe sternum protects the intrathoracic organs and contributes to chest wall mechanics, which makes reconstruction after tumor resection, trauma, or infection a demanding biomechanical problem. This study presents an in silico workflow for preselecting materials for sternal implants before physical prototyping. After a virtual resection, an anatomically conformal implant was designed and candidate biomaterials were screened in CES Selector using density, elastic modulus, fatigue strength, fracture toughness, toxicity, medical grade suitability, and MRI safety. A representative subset of the screened candidates was then compared by finite element modeling in terms of stress transfer and deformation. Seventeen candidates met the screening criteria. Ti-13Nb-13Zr showed an elastic modulus of about 80 GPa, and the titanium-based candidates showed deformation values of about 0.96 to 1.03 mm, whereas GF PEEK reached about 1.74 mm. The stress shielding index also showed that titanium-based materials remained on the implant-dominant side, while polymer-based materials shifted stress transfer toward bone. Taken together, the findings suggest that Ti-13Nb-13Zr offers the best overall balance for load-bearing sternal reconstruction, whereas PEEK-based systems may be more suitable within the present model for hybrid or adjunct designs. The proposed workflow can support early implant planning and guide future experimental and clinical studies.
dc.description.sponsorshipDelft University of Technology -- The article processing charge (APC) was funded by Delft University of Technology.
dc.identifier.doi10.3390/biomimetics11040251
dc.identifier.issn2313-7673
dc.identifier.issue4
dc.identifier.pmid42041481
dc.identifier.scopus2-s2.0-105037007949
dc.identifier.scopusqualityN/A
dc.identifier.urihttp://dx.doi.org/10.3390/biomimetics11040251
dc.identifier.urihttps://hdl.handle.net/20.500.12403/8451
dc.identifier.volume11
dc.identifier.wosWOS:001749916000001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMDPI
dc.relation.ispartofBiomimetics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260820
dc.subjectSternum Implant
dc.subjectBioinspired Design
dc.subjectCes Selector
dc.subjectBiomaterial Selection
dc.subjectFinite Element Analysis
dc.subjectThoracic Reconstruction
dc.titleBioinspired Sternal Implant Design for Generic Anatomical Reconstruction: An In Silico Framework for Material Selection and Biomechanical Validation
dc.typeArticle

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