Ultrasound assisted choline chloride-based deep eutectic solvent extraction of bioactive compounds from salsify (Tragopogon buphthalmoides (DC.) boiss. Var. Latifolius Boiss.): A Box-Behnken design approach for

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dc.contributor.authorYilmaz, Ozlem
dc.contributor.authorAbca, Tugba Elbir
dc.contributor.authorKamiloglu, Aybike
dc.contributor.authorKutlu, Naciye
dc.date.accessioned2024-10-04T18:54:07Z
dc.date.available2024-10-04T18:54:07Z
dc.date.issued2024
dc.departmentBayburt Üniversitesien_US
dc.description.abstractThis study aimed to investigate the ultrasound -assisted extraction of bioactive compounds from salsify using deep eutectic solvents (DESs) with different molar ratios. For this reason, total phenolic (TPC), total flavonoid (TFC) compounds, and antioxidant activities (1,1-diphenyl-2-picrilhydrazyl radical scavenging activity (DPPH center dot), and ferric reducing antioxidant power (FRAP)) of extracts prepared with DES were investigated with an experimental design and optimization study conducted for this purpose. An extraction time of 40.15 min was determined as the optimal condition. Under these conditions, a molar ratio of 3:1 (acetic acid:choline chloride) and a water ratio of 42.17 % provided the highest phenolic/flavonoid compounds and antioxidant activity. Correlations between water ratio, molar ratio, and sonication extraction time were determined using principal component analysis (PCA). In conditions where TPC, FRAP, and DPPH center dot were high according to PCA, it can be concluded that the extraction time, water ratio, and molar ratio are at high levels; contrarily, TFC is at a low level. In conclusion, ultrasound -assisted extraction using DES proved effective for salsify. Therefore, choline chloride -based DESs, can be recommended as environmentally friendly green solvents and an alternative to organic solvents for the extraction of bioactive compounds from salsify.en_US
dc.identifier.doi10.1016/j.microc.2024.110218
dc.identifier.issn0026-265X
dc.identifier.issn1095-9149
dc.identifier.scopus2-s2.0-85186187759en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.microc.2024.110218
dc.identifier.urihttp://hdl.handle.net/20.500.12403/3864
dc.identifier.volume199en_US
dc.identifier.wosWOS:001199053400001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofMicrochemical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBioactive compoundsen_US
dc.subjectDeep eutectic solventen_US
dc.subjectSalsifyen_US
dc.subjectUltrasonicationen_US
dc.subjectResponse surface methodologyen_US
dc.titleUltrasound assisted choline chloride-based deep eutectic solvent extraction of bioactive compounds from salsify (Tragopogon buphthalmoides (DC.) boiss. Var. Latifolius Boiss.): A Box-Behnken design approach foren_US
dc.typeArticleen_US

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