Synthesis of two alnustone-like natural diarylheptanoids via 4+3 strategy
Küçük Resim Yok
Tarih
2009
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The first total synthesis of (4E,6E)-1,7-bis(3,4-dihydroxyphenyl)-hepta-4, 6-dien-3-one and an alternative synthesis of (4E,6E)-1,7-bis(4-hydroxyphenyl)- hepta-4,6-dien-3-one, two natural diarylheptanoids, mainly based on Claisen-Schmidt condensation were described. The crucial steps of the syntheses were the condensation of OH-protected 4-aryl-2-butanones with OH-protected 3-aryl-acrylaldehydes by the in situ enamination and then deprotection of OH groups to give the corresponding natural diarylheptanoids. Copyright © Taylor & Francis Group, LLC.
Açıklama
Anahtar Kelimeler
1,7-Bis(3,4-dihydroxyphenyl)-hepta-4,6-dien-3-one, 1,7-bis(4-hydroxyphenyl)- hepta-4, 6-dien-3-one, Claisen-Schmidt condensation, diarylheptanoid, in situ enamination, synthesis, 1,7 bis(3,4 dihydroxyphenyl) hepta 4,6 dien 3 one, 1,7 bis(4 hydroxyphenyl) hepta 4,6 dien 3 one, alnustone, natural product, unclassified drug, amination, article, Claisen condensation, deprotection reaction, drug structure, drug synthesis, proton nuclear magnetic resonance, 1,7-Bis(3,4-dihydroxyphenyl)-hepta-4,6-dien-3-one, 1,7-bis(4-hydroxyphenyl)- hepta-4, 6-dien-3-one, Claisen-Schmidt condensation, diarylheptanoid, in situ enamination, synthesis, 1,7 bis(3,4 dihydroxyphenyl) hepta 4,6 dien 3 one, 1,7 bis(4 hydroxyphenyl) hepta 4,6 dien 3 one, alnustone, natural product, unclassified drug, amination, article, Claisen condensation, deprotection reaction, drug structure, drug synthesis, proton nuclear magnetic resonance
Kaynak
Synthetic Communications
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
39
Sayı
9
