Understanding the Functionality of Probiotics on the Edge of Artificial Intelligence (AI) Era

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dc.authorid0000-0001-6576-0084
dc.authorid0000-0002-3507-3272
dc.authorid0000-0001-8334-0403
dc.authorid0000-0001-6681-0944
dc.contributor.authorAsar, Remziye
dc.contributor.authorErenler, Sinem
dc.contributor.authorDevecioglu, Dilara
dc.contributor.authorIspirli, Humeyra
dc.contributor.authorKarbancioglu-Guler, Funda
dc.contributor.authorOzturk, Hale Inci
dc.contributor.authorDertli, Enes
dc.date.accessioned2026-02-28T12:18:15Z
dc.date.available2026-02-28T12:18:15Z
dc.date.issued2025
dc.departmentBayburt Üniversitesi
dc.description.abstractThis review focuses on the potential utilization of artificial intelligence (AI) tools to deepen our understanding of probiotics, their mode of action, and technological characteristics such as survival. To that end, this review provides an overview of the current knowledge on probiotics as well as next-generation probiotics. AI-aided omics technologies, including genomics, transcriptomics, and proteomics, offer new insights into the genetic and functional properties of probiotics. Furthermore, AI can be used to elucidate key probiotic activities such as microbiota modulation, metabolite production, and immune system interactions to enable an improved understanding of their health impacts. Additionally, AI technologies facilitate precision in identifying probiotic health impacts, including their role in gut health, anticancer activity, and antiaging effects. Beyond health applications, AI can expand the technological use of probiotics, optimizing storage survival and broadening biotechnological approaches. In this context, this review addresses how AI-driven approaches can be facilitated by strengthening the evaluation of probiotic characteristics, explaining their mechanisms of action, and enhancing their technological applications. Moreover, the potential of AI to enhance the precision of probiotic health impact assessments and optimize industrial applications is highlighted, concluding with future perspectives on the transformative role of AI in probiotic research.
dc.identifier.doi10.3390/fermentation11050259
dc.identifier.issn2311-5637
dc.identifier.issue5
dc.identifier.scopus2-s2.0-105006758918
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3390/fermentation11050259
dc.identifier.urihttps://hdl.handle.net/20.500.12403/6188
dc.identifier.volume11
dc.identifier.wosWOS:001496064600001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherMdpi
dc.relation.ispartofFermentation-Basel
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260218
dc.subjectomics technologies
dc.subjectbiotechnological optimization
dc.subjectAI-driven probiotic research
dc.subjectprecision health
dc.subjectmicrobiota modulation
dc.subjectmetabolite production
dc.subjectviability
dc.titleUnderstanding the Functionality of Probiotics on the Edge of Artificial Intelligence (AI) Era
dc.typeReview Article

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