Deep Eutectic Solvents as Sustainable Media for Efficient Recovery of Phenolics From Black (Lycium ruthenicum Murr.) and Red (Lycium barbarum Lam.) Goji Berries: Optimization and Functional Evaluation

dc.contributor.authorGercek, Yusuf Can
dc.contributor.authorKutlu, Naciye
dc.contributor.authorCelik, Saffet
dc.contributor.authorBayram, Sinan
dc.contributor.authorCevik, Berke
dc.contributor.authorBasturk, Fatma Nur
dc.contributor.authorBayram, Nesrin Ecem
dc.date.accessioned2026-09-01T15:52:36Z
dc.date.available2026-09-01T15:52:36Z
dc.date.issued2026
dc.departmentBayburt Üniversitesi
dc.description.abstractDeep eutectic solvents (DESs) have been frequently preferred over the past decade as alternatives to conventional solvents for the extraction of bioactive compounds from natural products. Meanwhile, black and red goji berries are widely consumed as functional foods due to their many functional properties reported in the literature. The aim of this study is to evaluate the effectiveness of different DESs in the extraction of individual phenolic compounds from goji berry (Lycium barbarum and L. ruthenicum) fruits, to determine the most suitable DES, and to optimize the extraction conditions. The DES that provided the highest yield in the extraction of individual phenolic compounds from L. barbarum was determined to be proline:citric acid (DES6 - a total of approximately 33,545 & micro;g/kg), while for L. ruthenicum it was choline chloride:acetic acid (DES3 - a total of approximately 37,496 & micro;g/kg). Rutin was the predominant phenolic compound in both species. DESs provided a higher phenolic yield compared to ethanol and water. In addition, L. ruthenicum exhibited higher total phenolics, flavonoids, proanthocyanidins, and antioxidant activity compared to L. barbarum. These findings reveal that DESs are a green, efficient, and sustainable alternative for the extraction of phenolic compounds from goji berries.
dc.description.sponsorshipScientific Research Projects Coordination Unit of Istanbul University [FBA-2023-40231] -- This study was funded by the Scientific Research Projects Coordination Unit of Istanbul University (Project No.: FBA-2023-40231). This study includes the results of Berke Cevik's master's thesis.
dc.identifier.doi10.1111/1750-3841.71161
dc.identifier.issn0022-1147
dc.identifier.issn1750-3841
dc.identifier.issue6
dc.identifier.orcid0000-0002-4075-8823
dc.identifier.pmid42240001
dc.identifier.scopus2-s2.0-105040964137
dc.identifier.scopusqualityQ2
dc.identifier.urihttp://dx.doi.org/10.1111/1750-3841.71161
dc.identifier.urihttps://hdl.handle.net/20.500.12403/8494
dc.identifier.volume91
dc.identifier.wosWOS:001810770200001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofJournal of Food Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260820
dc.subjectAnthocyanin
dc.subjectGoji Berry
dc.subjectGreen Solvent
dc.subjectLycium
dc.subjectNades
dc.subjectPhenolic
dc.titleDeep Eutectic Solvents as Sustainable Media for Efficient Recovery of Phenolics From Black (Lycium ruthenicum Murr.) and Red (Lycium barbarum Lam.) Goji Berries: Optimization and Functional Evaluation
dc.typeArticle

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