Phytochemical analysis and biological evaluation of essential oils and extracts from Heracleum pastinacifolium subsp. incanum (Boiss. & A.Huet) PHDavis, an endemic plant from Turkey

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dc.contributor.authorYuca, Hafize
dc.contributor.authorSefali, Abdurrahman
dc.contributor.authorAydin, Bilge
dc.contributor.authorKaradayi, Mehmet
dc.contributor.authorGulsahin, Yusuf
dc.contributor.authorYazici, Aysenur
dc.contributor.authorKarakaya, Songul
dc.date.accessioned2024-10-04T18:52:39Z
dc.date.available2024-10-04T18:52:39Z
dc.date.issued2024
dc.departmentBayburt Üniversitesien_US
dc.description.abstractEssential oil content of and phenolic compounds flower-fruit, root, and aerial parts of Heracleum pastinacifolium subsp. incanum were analysed by GC/MS and LC/MS methods, respectively. Antidiabetic, anticholinesterase, and antioxidant activities of flower-fruit, root, aerial parts methanol extracts were evaluated. Apiole (35.0%), myristicine (72.2%), and myristicine (15.1%) were found as major compounds of fruit-flower mixture, root, aerial part essential oils, respectively. Hesperidin was found the highest amount in aerial part and flower-fruit extracts with 8904.2621 ng/mL and 11558.3634 ng/mL values, respectively. Fruit-flower extract showed the highest activity against alpha-glucosidase (24%). Root extract demonstrating the highest activity (18%) against AChE enzyme. Flowers-fruits mixture methanol extract had a higher % inhibition value on ABTS(+) and DPPH center dot. Flowers-fruits mixture methanol extract was rich in total phenol, total tannin, and protein content. All the extracts were determined as genetoxically safe according to the results of Ames/Salmonella, Escherichia coli WP2 and Allium cepa assays.en_US
dc.identifier.doi10.1080/14786419.2024.2372661
dc.identifier.issn1478-6419
dc.identifier.issn1478-6427
dc.identifier.pmid38962953en_US
dc.identifier.scopus2-s2.0-85197876348en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1080/14786419.2024.2372661
dc.identifier.urihttp://hdl.handle.net/20.500.12403/3599
dc.identifier.wosWOS:001263044300001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofNatural Product Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlzheimer'sen_US
dc.subjectdiabetesen_US
dc.subjectgenotoxicen_US
dc.subjectHeracleum pastinacifolium subsp. incanumen_US
dc.subjecthesperidinen_US
dc.subjectmyristicineen_US
dc.titlePhytochemical analysis and biological evaluation of essential oils and extracts from Heracleum pastinacifolium subsp. incanum (Boiss. & A.Huet) PHDavis, an endemic plant from Turkeyen_US
dc.typeArticleen_US

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