Recovery of Polyphenols Using Pressurized Hot Water Extraction (PHWE) from Black Rosehip Followed by Encapsulation for Increased Bioaccessibility and Antioxidant Activity

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dc.authoridKasapoglu, Kadriye Nur/0000-0001-6070-4948
dc.authoridGultekin-Ozguven, Mine/0000-0002-2073-8075
dc.authoridDemircan, Evren/0000-0001-8533-6037
dc.authoridOzcelik, Beraat/0000-0002-1810-8154
dc.authoridARSLANER, AYLA/0000-0002-2777-9697
dc.contributor.authorKasapoglu, Kadriye Nur
dc.contributor.authorDemircan, Evren
dc.contributor.authorGultekin-Ozguven, Mine
dc.contributor.authorKruger, Johanita
dc.contributor.authorFrank, Jan
dc.contributor.authorArslaner, Ayla
dc.contributor.authorOzcelik, Beraat
dc.date.accessioned2024-10-04T18:52:46Z
dc.date.available2024-10-04T18:52:46Z
dc.date.issued2022
dc.departmentBayburt Üniversitesien_US
dc.description.abstractIn this work, pressurized hot water extraction (PHWE) of hydrophilic polyphenols from black rosehip fruit was maximized using response surface methodology for simultaneous optimization in terms of extraction yield, total antioxidant capacity, total (poly)phenols, catechin, total monomeric anthocyanins, and cyanidin-3-O-glucoside. Extraction parameters, including temperature (X1: 40-80 degrees C) and the solvent-to-solid ratio (X2: 10-40 mL/g), were investigated as independent variables. Experimentally obtained values were fitted to a second-order polynomial model, and optimal conditions were determined using multiple regression analysis and analysis of variance. The black rosehip extract (BRE) obtained at optimized PHWE conditions was further encapsulated in biopolymer-coated liposomes and spray dried to enhance its processing and digestive stability. After reconstitution, the fabricated particles had an average size of 247-380 nm and a zeta-potential of 15-45 mV. Moreover, encapsulation provided remarkable protection of the phenolics under in vitro gastrointestinal digestion conditions, resulting in up to a 5.6-fold more phenolics in the bioaccessible fraction, which also had 2.9-8.6-fold higher antioxidant activity compared to the nonencapsulated BRE. In conclusion, PHWE in combination with a biopolymer coating is a potent method for the production of stable and safe edible natural extracts for the delivery of (poly)phenolic compounds in food and dietary supplements.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey [2214-A, 53325897-115.02-166509]en_US
dc.description.sponsorshipK.N.K was supported by The Scientific and Technological Research Council of Turkey under the program of 2214-A International Research Fellowship for PhD Students (application number: 53325897-115.02-166509).en_US
dc.identifier.doi10.3390/molecules27206807
dc.identifier.issn1420-3049
dc.identifier.issue20en_US
dc.identifier.pmid36296399en_US
dc.identifier.scopus2-s2.0-85140730825en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.3390/molecules27206807
dc.identifier.urihttp://hdl.handle.net/20.500.12403/3643
dc.identifier.volume27en_US
dc.identifier.wosWOS:000873215200001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofMoleculesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectgreen extractionen_US
dc.subjectresponse surface modelingen_US
dc.subjectRosa pimpinellifoliaen_US
dc.subjectin vitro digestionen_US
dc.subjectliposomesen_US
dc.subjectspray dryingen_US
dc.subjectchitosanen_US
dc.subjectwhey proteinen_US
dc.titleRecovery of Polyphenols Using Pressurized Hot Water Extraction (PHWE) from Black Rosehip Followed by Encapsulation for Increased Bioaccessibility and Antioxidant Activityen_US
dc.typeArticleen_US

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