The role of biotics and bioactive compounds in sports injuries: a narrative review

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dc.contributor.authorSahin-Demirci, Kezban
dc.contributor.authorDal, Nursel
dc.contributor.authorGonen-Colak, Buket
dc.contributor.authorAkman, Onur
dc.contributor.authorRaposa, Bence
dc.contributor.authorAgagunduz, Duygu
dc.date.accessioned2026-09-01T15:52:34Z
dc.date.available2026-09-01T15:52:34Z
dc.date.issued2026
dc.departmentBayburt Üniversitesi
dc.description.abstractSports injuries affect not just the physical, but also the psychological, social, and professional aspects of athletes' lives. Preventive strategies, nutrition, and nutritional supplements-especially biotics and bioactive compounds-are crucial for recovery and may help prevent injury recurrence. This review examines biotics and bioactive compounds that may be effective on sports injuries, revealing their potential benefits and safety of use. Using a comparative and interpretive approach, the pertinent literature was thoroughly examined for this review, with a special focus on clinical and preclinical research conducted within the last 5 years. Bioactive compounds and biotics (prebiotics: indigestible substances that support beneficial bacteria; probiotics: live beneficial microorganisms; postbiotics: bioactive microbial metabolites) can improve sports-related injuries by affecting inflammation, mitochondrial function, biogenesis, oxidative stress, and atrophy. Biotics achieve these systemic effects by improving intestinal barrier function and modulating the microbiota. Current literature indicates that some compounds show promise for treating sports injuries, but human study evidence is limited. Animal models provide useful insights for future research. Finally, polyphenolic compounds, amino acids/peptides, and w-3 fatty acids, thanks to their anti-inflammatory and antioxidant properties, can indirectly contribute to muscle regeneration and cell repair, thus supporting the recovery process in athletes. However, it is still too early to make recommendations regarding the use of biotics and bioactive compounds in sports injuries.
dc.identifier.doi10.3389/fnut.2026.1813030
dc.identifier.issn2296-861X
dc.identifier.pmid42221774
dc.identifier.scopus2-s2.0-105041414336
dc.identifier.scopusqualityN/A
dc.identifier.urihttp://dx.doi.org/10.3389/fnut.2026.1813030
dc.identifier.urihttps://hdl.handle.net/20.500.12403/8460
dc.identifier.volume13
dc.identifier.wosWOS:001776862700001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherFrontiers Media Sa
dc.relation.ispartofFrontiers in Nutrition
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260820
dc.subjectPolyphenols
dc.subjectProbiotics
dc.subjectSports Injuries
dc.subjectSports Nutrition
dc.subjectSupplementation
dc.titleThe role of biotics and bioactive compounds in sports injuries: a narrative review
dc.typeReview Article

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