Mindfulness-based cognitive therapy for adherence of immunosuppressive treatment in liver transplant recipients: A randomized controlled trial

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dc.contributor.authorBulbuloglu, Semra
dc.contributor.authorGunes, Huseyin
dc.date.accessioned2024-10-04T18:52:30Z
dc.date.available2024-10-04T18:52:30Z
dc.date.issued2024
dc.departmentBayburt Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to analyze the effects of mindfulness-based cognitive therapy on the adherence of liver transplant recipients to immunosuppressive therapy with a randomized controlled design. Method: This randomized controlled trial was performed with 120 liver transplant recipients hospitalized at the liver transplant department of a research and practice hospital (n = 120). While we administered no intervention to the patients in the control group (n = 60), we provided Mindfulness-Based Cognitive Therapy to those in the experimental group (n = 60). We used the Mindful Attention Awareness Scale and the Immunosuppressant Therapy Adherence Scale to collect data. We utilized descriptive statistics, paired-samples t-tests, independent samples t-tests, one-way analysis of variance, and chi-squared tests to analyze the data. Results: After the intervention, the immunosuppressive therapy adherence levels of the experimental group increased significantly (p < 0.01). On the other hand, the control group had significantly higher adherence to immunosuppressive therapy and significantly higher levels of mindfulness in the pretest phase than it did in the posttest phase (p < 0.01). Conclusions: Complete adherence to immunosuppressive therapy is imperative for the prevention of graft rejection in liver transplant recipients. In our study, the experimental group equipped with enhanced mindfulness had higher adherence to immunosuppressive therapy. Therefore, the use of Mindfulness-Based Cognitive Therapy in the promotion of adherence to immunosuppressive therapy is recommended.en_US
dc.identifier.doi10.1016/j.explore.2024.01.005
dc.identifier.issn1550-8307
dc.identifier.issn1878-7541
dc.identifier.issue5en_US
dc.identifier.pmid38245470en_US
dc.identifier.scopus2-s2.0-85183093480en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1016/j.explore.2024.01.005
dc.identifier.urihttp://hdl.handle.net/20.500.12403/3490
dc.identifier.volume20en_US
dc.identifier.wosWOS:001266708100001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofExplore-The Journal of Science and Healingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLiver transplant recipientsen_US
dc.subjectMindfulness-based cognitive therapyen_US
dc.subjectLiver transplantationen_US
dc.subjectMindfulnessen_US
dc.subjectAdherence to immunosuppressive therapyen_US
dc.titleMindfulness-based cognitive therapy for adherence of immunosuppressive treatment in liver transplant recipients: A randomized controlled trialen_US
dc.typeArticleen_US

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