Expanding Layers of Bacteriocin Applications: From Food Preservation to Human Health Interventions

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dc.authorid0009-0002-8910-2902
dc.authorid0000-0002-0141-0058
dc.authorid0000-0003-0624-9352
dc.authorid0000-0002-1837-5682
dc.authorid0000-0002-7333-1295
dc.contributor.authorDemirgul, Furkan
dc.contributor.authorKaya, Halil Ibrahim
dc.contributor.authorUcar, Redife Aslihan
dc.contributor.authorMitaf, Naciye Afranur
dc.contributor.authorSimsek, Omer
dc.date.accessioned2026-02-28T12:18:15Z
dc.date.available2026-02-28T12:18:15Z
dc.date.issued2025
dc.departmentBayburt Üniversitesi
dc.description.abstractBacteriocins, ribosomally synthesized by bacteria, have long been recognized for their role in ensuring food safety and security due to their antibacterial effects against foodborne pathogens and spoilage bacteria. However, recent advancements have unveiled their expanding potential beyond food applications, with increasing evidence of their efficacy against clinically significant pathogenic bacteria, biofilm formation, viral infections, and even cancer. These emerging discoveries have continuously added new layers to the application of bacteriocins, extending their relevance from food preservation to broader human health interventions. To further harness this expanding potential, various innovative strategies have been developed to overcome traditional limitations associated with bacteriocin use. Instead of directly employing bacteriocins or bacteriocin-producing bacterial cultures, novel approaches, such as incorporating them into films and packaging materials or coupling them with nanoparticles, have demonstrated enhanced effectiveness. In this review, we examine the evolving landscape of bacteriocin applications and shed light on the expanding functional spectrum of bacteriocins for both food safety and human health, although some important challenges and limitations remain. By analyzing the recent literature and innovative technological advancements, we highlight how bacteriocins are continuously evolving, opening new frontiers for their use and reinforcing their significance beyond their conventional roles.
dc.identifier.doi10.3390/fermentation11030142
dc.identifier.issn2311-5637
dc.identifier.issue3
dc.identifier.scopus2-s2.0-105001298448
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3390/fermentation11030142
dc.identifier.urihttps://hdl.handle.net/20.500.12403/6187
dc.identifier.volume11
dc.identifier.wosWOS:001452299600001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherMdpi
dc.relation.ispartofFermentation-Basel
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260218
dc.subjectbacteriocins
dc.subjectfood safety
dc.subjecthealth applications
dc.subjectantimicrobial peptides
dc.subjectinnovative bacteriocin delivery
dc.titleExpanding Layers of Bacteriocin Applications: From Food Preservation to Human Health Interventions
dc.typeReview Article

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