Investigation of biological activities of plant extract and green synthesis silver nanoparticles obtained from Gilaburu (Viburnum opulus L.) fruits

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dc.authoridSahin, Birgutay/0000-0003-0584-6075
dc.contributor.authorSahin, Birgutay
dc.contributor.authorBulbul, Ali Savas
dc.contributor.authorCelik, I. Seyfettin
dc.contributor.authorKorkmaz, Nesrin
dc.contributor.authorKaradag, Ahmet
dc.date.accessioned2024-10-04T18:51:10Z
dc.date.available2024-10-04T18:51:10Z
dc.date.issued2022
dc.departmentBayburt Üniversitesien_US
dc.description.abstractIn this study, biological activities of silver nanoparticles (AgNP) synthesized by green synthesis method using the fruit extract of Gilaburu (Viburnum opulus L.) plant were investigated. The characterization of the synthesized AgNPs was performed by ultraviolet visible region spectroscopy (UV-Vis), Fourier transform -infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and X-ray diffraction (XRD) techniques. The crystal size was found to be 52.32 nm when the XRD data were calculated with the Debye-Scherrer's equation. The antimicrobial activities of extract and AgNPs were investigated by microdilution and disk diffusion methods. Antibiofilm activities were examined by the crystal violet technique. The cytotoxic effects of the extract and AgNPs against MCF-7 (human breast cancer) and HUVEC (human umbilical vein endothelial cells) cell lines were evaluated by MTT assay. The IC50 values for the HUVEC line were found to be 0.97 mg/mL (AgNP) and 85.24 mg/mL (extract), while the IC50 values for the MCF-7 line were determined as 0.022 mu g/mL (AgNP) and 0.021 mu g/mL (extract). To our knowledge, this is the first report to comprehensively examine the biological activities of V. opulus L. extract and biosynthetic AgNPs.en_US
dc.description.sponsorshipKahramanmaras Sutcu Imam University Scientific Research Projects Unit [2019/6-25M]en_US
dc.description.sponsorshipThis work was supported by a grant from the Kahramanmaras Sutcu Imam University Scientific Research Projects Unit, Project Number: 2019/6-25M.en_US
dc.identifier.doi10.3906/kim-2108-48
dc.identifier.endpage235en_US
dc.identifier.issn1300-0527
dc.identifier.issue1en_US
dc.identifier.pmid38143882en_US
dc.identifier.scopus2-s2.0-85126109085en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage224en_US
dc.identifier.trdizinid530117en_US
dc.identifier.urihttps://doi.org/10.3906/kim-2108-48
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/530117
dc.identifier.urihttp://hdl.handle.net/20.500.12403/3415
dc.identifier.volume46en_US
dc.identifier.wosWOS:000737140600001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal of Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiological activityen_US
dc.subjectfruit extracten_US
dc.subjectgreen synthesisen_US
dc.subjectHUVEC (human umbilical vein endothelial cells)en_US
dc.subjectMCF-7 (human breast cancer)en_US
dc.subjectViburnum opulus Len_US
dc.titleInvestigation of biological activities of plant extract and green synthesis silver nanoparticles obtained from Gilaburu (Viburnum opulus L.) fruitsen_US
dc.typeArticleen_US

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