Gastrointestinal stability and bioactivity of propolis from diverse origins

Küçük Resim Yok

Tarih

2026

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Springer

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Propolis is a chemically complex bee product whose biological properties depend on its botanical and geographical origin. However, little is known about how gastrointestinal digestion affects its phenolic profile and bioactivity. In this study, twelve propolis samples from eight countries were evaluated for phenolic and flavonoid contents, antioxidant capacity (FRAP, ABTS+center dot), and urease inhibition before and after simulated gastric digestion. RP-HPLC-PDA identified 26 phenolic compounds showing substantial compositional diversity. Turkish Bolu propolis retained the highest post-gastric FRAP value, while several samples (BBP, AFP) maintained or enhanced urease inhibition. PCA and HCA highlighted origin-dependent differentiation, identifying digestive stability as a key variable for functional potential.

Açıklama

Anahtar Kelimeler

Propolis, Gastrointestinal Stability, Antioxidant Activity, Urease Inhibition, Pca, Hca

Kaynak

European Food Research and Technology

WoS Q Değeri

Q2

Scopus Q Değeri

Q1

Cilt

252

Sayı

4

Künye