Gastrointestinal stability and bioactivity of propolis from diverse origins

dc.contributor.authorCan, Zehra
dc.contributor.authorCelebi, Zeynep Berin
dc.contributor.authorTunca, Erol
dc.contributor.authorKolayli, Sevgi
dc.contributor.authorSevin, Sedat
dc.contributor.authorTutun, Hidayet
dc.date.accessioned2026-09-01T15:53:10Z
dc.date.available2026-09-01T15:53:10Z
dc.date.issued2026
dc.departmentBayburt Üniversitesi
dc.description.abstractPropolis is a chemically complex bee product whose biological properties depend on its botanical and geographical origin. However, little is known about how gastrointestinal digestion affects its phenolic profile and bioactivity. In this study, twelve propolis samples from eight countries were evaluated for phenolic and flavonoid contents, antioxidant capacity (FRAP, ABTS+center dot), and urease inhibition before and after simulated gastric digestion. RP-HPLC-PDA identified 26 phenolic compounds showing substantial compositional diversity. Turkish Bolu propolis retained the highest post-gastric FRAP value, while several samples (BBP, AFP) maintained or enhanced urease inhibition. PCA and HCA highlighted origin-dependent differentiation, identifying digestive stability as a key variable for functional potential.
dc.description.sponsorshipBayburt University -- Open access funding provided by the Scientific and Technological Research Council of Turkiye (TUB & Idot;TAK).
dc.identifier.doi10.1007/s00217-026-05104-w
dc.identifier.issn1438-2377
dc.identifier.issn1438-2385
dc.identifier.issue4
dc.identifier.scopus2-s2.0-105033442667
dc.identifier.scopusqualityQ1
dc.identifier.urihttp://dx.doi.org/10.1007/s00217-026-05104-w
dc.identifier.urihttps://hdl.handle.net/20.500.12403/8566
dc.identifier.volume252
dc.identifier.wosWOS:001717804200001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofEuropean Food Research and Technology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260820
dc.subjectPropolis
dc.subjectGastrointestinal Stability
dc.subjectAntioxidant Activity
dc.subjectUrease Inhibition
dc.subjectPca
dc.subjectHca
dc.titleGastrointestinal stability and bioactivity of propolis from diverse origins
dc.typeArticle

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